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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Fusion protein of Human TAB3
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q8N5C8
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,WB,IHC;ELISA:1:2000-1:10000,WB:1:1000-1:5000,IHC:1:50-1:200
- 浓度:
>95%,Antigen affinity purification
- 靶点:
TAB3
- 抗体英文名:
TAB3 Antibody
- 抗体名:
TGF-beta-activated kinase 1-binding protein 3 antibody
- 规格:
100μl/50μl
| 规格: | 100μl | 产品价格: | ¥1980.0 |
|---|---|---|---|
| 规格: | 50μl | 产品价格: | ¥1100.0 |
保存缓冲液
-20℃, pH7.4 PBS, 0.05% NaN3, 40% Glycerol功能
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验. Y., and Yao, S. Q. (2002) Antibody-based fluorescence detection of kinase activity on a peptide array. Bioorg.Med. Chem. Lett. 1 2 , 2085-2088. 7. Fukunaga, R. and Hunter, T. (1997) M N K 1 , a n e w M A P kinase-activated protein kinase
-89 个氨基酸的N末端调节区的部分p21-activated kinase (PAK-1)相结合。PAK-1的这个区域,被认为是p21偶联区域即P21binding domain (PBD),特异性的与活性形式的Rac1相作用,最终提供了一个优秀的工具以分离细胞样本中的活性Rac1. 细胞被镁盐缓冲溶液( magnesium lysis buffer)所裂解; 接着裂解液需要采用GST-agarose beads (not provided)进行预清除.在这一步,少量的细胞裂解液能够储存
TRAF‐Mediated TNFR‐Family Signaling
. Science 277:818‐821. Shi, C.S. and Kehrl, J.H. 2003. Tumor necrosis factor (TNF)‐induced germinal center kinase‐related (GCKR) and stress‐activated protein kinase (SAPK
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