TAB3 抗体-TAB3 Antibody

TAB3 抗体，TAB3 Antibody，TAB3 抗体,TAB3 Antibody

产品名称：TAB3 抗体-TAB3 Antibody

产品货号：PSI-3391-0.02mg

产品规格：0.02mg

背景资料：TAB3 Antibody: TAB3 functions in the NF-kappaB signal transduction pathway. It and the similar and functionally redundant protein TAB2, form a ternary complex with the protein kinase TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1; upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibit autophagy, while their depletion triggers it, suggesting that TAB2 and TAB3 act as a control point for autophagy.

保存建议：TAB3 抗体-TAB3 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, IHC-P

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