Sample:
NIH/3T3(Mouse) Cell Lysate at 30 ug
Primary: Anti-KIF5C (bs-17061R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 109 kD
Observed band size: 109 kD
- ￥1180 - 2800
- Bioss
- bs-17061R
- 2025年10月24日
- 产品信息以Bioss网站为准
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产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-17061R |
| 英文名称 | KIF5C Rabbit pAb |
| 中文名称 | 驱动蛋白家族成员5C抗体 |
| 英文别名 | KIFC5C; FLJ44735; KIAA0531; KIF5C_HUMAN; KIF 5C; KIF5C; KIF5C protein; Kinesin family member 5C; Kinesin heavy chain neuron specific 2; Kinesin heavy chain neuron specific; Kinesin5C; KINN; MGC111478; NKHC 2; NKHC; NKHC2. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Chicken, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human KIF5C |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 109 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin |
| 亚基 | Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 and KLC3 (By similarity). Interacts with TRAK1. |
| 亚细胞定位 | Cytoplasm； cytoskeleton. |
| 组织特异性 | Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary. |
| 相似性 | Belongs to the kinesin-like protein family. Kinesin subfamily. Contains 1 kinesin-motor domain. |
| 功能 | Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Neuronal kinesin heavy chain 2 (NKHC2) is a 1,032 amino acid protein that is part of the kinesin superfamily which consists of the heavy chains of conventional kinesin. NKHC is expressed throughout the central nervous system, but is highly expressed in certain subsets of neurons. NKHC has a unique C-terminal stretch of 69 amino acids and interacts with dystrobrevin, an adaptor/scaffolding protein. This interaction may play a role in the transport and targeting of components of the dystrophin-associated protein complex to precice sites in the cell. NKHC may also be involved in the microtubule-dependent slow axonal transport of neurofilament proteins during the maturation of neuronal cells. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KIF5C) Polyclonal Antibody, Unconjugated (bs-17061R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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文献和实验该产品被引用文献
[IF={{ 8.9 }}] {Guo Yang. et al. Mechanisms of electroacupuncture-induced neuroprotection in acute stroke rats: the role of astrocyte-mediated mitochondrial transfer. CELL COMMUN SIGNAL. 2025 Dec;23(1):1-20} {WB} {Rat}
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KIF5C Rabbit pAb(bs-17061R)-50ul/100ul/200ul
￥1180 - 2800
