Endokinin-A/B Rabbit pAb(bs-16470R)-50ul/100ul/200ul

Endokinin-A/B Rabbit pAb(bs-16

470R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-16470R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-16470R
    英文名称Endokinin-A/B Rabbit pAb
    中文名称Endokinin-A/B抗体
    英文别名EK; Endokinin; HK 1; EKA/B; HK1; TKN4_HUMAN; Preprotachykinin C; TAC4; Tachykinin 4(hemokinin); Tachykinin 4; Endokinin-A.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Hemokinin 1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量5.0 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Secreted.
    组织特异性Expressed at low levels in the uterus of both pregnant and non-pregnant women. Isoform 1 is found only in the adrenal gland and fetal liver. Isoform 2 is found in heart, liver, bone marrow, prostate, adrenal gland and testis. Isoform 3 and isoform 4 are expressed predominantly in adrenal gland and placenta.
    相似性Belongs to the tachykinin family.
    功能Hemokinin 1 are from the Tachykinins family of proteins that are active peptides which excite neurons. They evoke behavioral responses and are potent vasodilators and secretagogues. Hemokinin 1 involved in contraction (directly or indirectly) of many smooth muscles. Hemokinin 1is cleaved in to three short peptides Edokinin A,B,C. Endokinin A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with Endokinin C. Endokinin A/B reduces arterial blood pressure and increases sperm motility.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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