ROR gamma T Rabbit pAb(bs-10647R)-50ul/100ul/200ul产品图
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ROR gamma T Rabbit pAb(bs-1064

7R)-50ul/100ul/200ul
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  • ￥1180 - 2800
  • Bioss已认证
  • bs-10647R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格：

      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-10647R
    英文名称ROR gamma T Rabbit pAb
    中文名称维甲酸相关孤儿受体γt抗体
    英文别名RORG_HUMAN; Nuclear receptor ROR-gamma; ROR gamma; NR1F3; RZRG; TOR; IMD42; RZR-GAMMA; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR-related orphan receptor C; Retinoid-related orphan receptor-gamma; ROR gamma T [Mus musculus]; nuclear receptor ROR-gamma isoform 2; RORgT;
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, Flow-Cyt=1ug/test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human, Chicken, Dog, Pig, Cow, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from mouse ROR gamma T
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量54 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Corticoid

    Epigenetics and Nuclear Signaling > Transcription > Transcription Factors

    Signal Transduction > Growth Factors/Hormones > Hormones

    亚细胞定位Nucleus (Probable).
    组织特异性Isoform 1: widely expressed in many tissues, including liver and adipose, and highly expressed in skeletal muscle. Isoform 2: Primarily expressed in immature thymocytes.
    相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
    功能Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T helper cells into Th17 cells. Regulate the expression of several components of the circadian clock.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}
    {Flow-Cyt}{1ug/test}

     

    产品细节图片1
    Sample:
    Muscle (mouse) Lysate at 40 ug
    Kidney (mouse) Lysate at 40 ug
    Primary: Anti- ROR gamma T (bs-10647R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
    Predicted band size: 54 kD
    Observed band size: 54 kD
    产品细节图片2
    Sample:
    Lane1: Mouse Muscle Lysates
    Lane2: Rat Muscle Lysates
    Primary: Anti-ROR Gamma (bs-10647R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 57 kD
    Observed band size: 50 kD

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    图标文献和实验
    该产品被引用文献
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    • Protocol for intracytoplasmic staining of cytokines for FACS analysis

      + 1% BSA, + 5% heat inactivated normal rabbit serum (HINRS). 9) Label with antibodies to surface molecules that are resistant to fixation (30 mins 4 deg C) eg. anti-CD4 (H129.19-Quantum Red; Sigma R 3637) for FL3 anti-CD44 (Pgp-1:IM

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    ROR gamma T Rabbit pAb(bs-10647R)-50ul/100ul/200ul
    ￥1180 - 2800