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Syntaxin 13 Rabbit pAb(bs-1137

8R)-50ul/100ul/200ul
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  • ￥1180 - 2800
  • Bioss已认证
  • bs-11378R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-11378R
    英文名称Syntaxin 13 Rabbit pAb
    中文名称神经突触素13抗体
    英文别名Syntaxin13; Syntaxin 13; Syntaxin-13; Syx13; Syx 13; Syx-13; CG11278; CT31479; Dm Syx13; ff16; l(3)01470; STX12_RAT.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Dog, Pig, Cow, Horse, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from rat Syntaxin 13
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量31 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Protein Trafficking > Vesicle Transport > SNAPs & SNAREs

    亚基Associates with the BLOC-1 complex. Interacts with BLOC1S6 (By similarity). Interacts with NAPA and SNAP23. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A.
    亚细胞定位Membrane. Golgi apparatus > trans-Golgi network membrane.
    组织特异性 Ubiquitous. Highly expressed in brain.
    相似性Belongs to the syntaxin family.
    Contains 1 t-SNARE coiled-coil homology domain.
    功能SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain C-terminal hydrophobic domains that direct them to their respective intracellular compartments. Syntaxin 12, also known as STX12, STX13 or STX14, is a 276 amino acid single-pass membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the Syntaxin family. Syntaxin 12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I). Found in recycling endosomes, Syntaxin 12 colocalizes with transferrin receptor and is encoded by a gene located on human chromosome 1.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    P‌‌araformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Syntaxin 13) Polyclonal Antibody, Unconjugated (bs-11378R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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    该产品被引用文献

    [IF={{ 4.4 }}] {Otero et al. Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function. (2014) J.Cell.Sci. 127:1537-49} {WB} {Mouse}

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      GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin

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    文献支持
    Syntaxin 13 Rabbit pAb(bs-11378R)-50ul/100ul/200ul
    ￥1180 - 2800