TMEM106B Rabbit pAb(bs-11694R)-50ul/100ul/200ul产品图
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TMEM106B Rabbit pAb(bs-11694R)

-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-11694R
  • 2026年10月14日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-11694R
    英文名称TMEM106B Rabbit pAb
    中文名称跨膜蛋白106B抗体
    英文别名Tmem106b; Transmembrane protein 106B; 2310036D22Rik; 5830455K21Rik; 6430519M21Rik; AI428776; AI661344; FLJ11273; LRRGT00101; MGC33727; MGC94135; T106B_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human TMEM106B
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量31 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurology process > Neurodegenerative disease

    Neuroscience > Neurology process > Neurodegenerative disease > Amyotrophic lateral sclerosis

    亚细胞定位Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein.
    组织特异性Expressed in frontal cortex.
    相似性Belongs to the TMEM106 family.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料TMEM106B is a 274 amino acid single-pass membrane protein that is encoded by a gene which maps to human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    _x000D_ Lane 1: Recombinant human TMEM106B protein, N-Trx-His(bs-42250P)
    _x000D_ Primary: Anti-TMEM106B (bs-11694R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 31 kDa
    _x000D_ Observed band size: 32 kDa

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    图标文献和实验
    该产品被引用文献
    [1]TMEM106B expression is reduced in Alzheimer's disease brains.
    PMID:24684749Alzheimers Res Ther2014-03-31
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    文献支持
    TMEM106B Rabbit pAb(bs-11694R)-50ul/100ul/200ul
    ¥1180 - 2800