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ASMTY Rabbit pAb(bs-6961R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-6961R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-6961R
    英文名称ASMTY Rabbit pAb
    中文名称松果体N甲基乙酰羟色胺抗体
    英文别名acetylserotonin methyltransferase(Y chromosome); acetylserotonin N-methyltransferase; Acetylserotonin O-methyltransferase; ASMT; ASMTY; HIOM_HUMAN; HIOMT; HIOMTY; Hydroxyindole O-methyltransferase.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse, Dog, Cow, Horse, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Dopamine transporter
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量38 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism

    Neuroscience > Neurotransmitter > Amino Acids

    Signal Transduction > Metabolism > Amino Acids

    组织特异性Expressed in the pineal gland (at protein level). In the retina, very low expression is found at the mRNA level (PubMed:7989373), and not at the protein level (PubMed:8574683).
    相似性Belongs to the methyltransferase superfamily.
    功能Produces melatonin (N-acetyl-5-methoxytryptamine) from N-acetylserotonin.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Most abundant in pineal gland, less in retina and brain, not in pigment epithelium.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample: Brain (Rat) Lysate at 40 ug
    Primary: Anti- ASMTY (bs-6961R) at 1/300 dilution
    Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution
    Predicted band size: 38 kD
    Observed band size: 38/45 kD

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    图标文献和实验
    该产品被引用文献

    [IF={{ 5.249 }}] {Zhang, WL.. et al. Expression of arylalkylamine n-acetyltransferase (AANAT) and acetylserotonin o-methyltransferase (ASMT) in the corpus luteum of pregnant sows and synthesis of melatonin in luteal cells. 2021 Nov 24} {WB,IHC} {Pig}

    [IF={{ 3.24 }}] {Herman, A. P., et al. "Central Interleukin-1β Suppresses the Nocturnal Secretion of Melatonin." Mediators of Inflammation 2016 (2016).} {WB} {="Others"}

    [IF={{ 2.71 }}] {Herman, A. P., et al. "Interleukin-1β Modulates Melatonin Secretion in Ovine Pineal Gland: Ex Vivo Study." BioMed Research International (2015).} {WB} {="Other Species"}

    [IF={{ 2.089 }}] {Huawei Wei. et al. Melatonin through blockade of Hif-1α signaling mediates the anti-fibrosis under hypoxia in canine Sertoli cells. REPROD BIOL. 2022 Dec;22:100677} {WB,IHC} {Dog}

    [IF={{ 10.3 }}] {Jinho Kim. et al. Biosynthesis of neuroprotective melatonin is dysregulated in Huntington's disease. J PINEAL RES. 2023 Sep;:e12909} {WB} {Human,Mouse}

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    文献支持
    ASMTY Rabbit pAb(bs-6961R)-50ul/100ul/200ul
    ¥1180 - 2800