ANT1+ANT2+ANT3+ANT4 Rabbit pAb(bs-9567R)-50ul/100ul/200ul
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ANT1+ANT2+ANT3+ANT4 Rabbit pAb

(bs-9567R)-50ul/100ul/200ul
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  • ￥1180 - 2800
  • Bioss已认证
  • bs-9567R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-9567R
    英文名称ANT1+ANT2+ANT3+ANT4 Rabbit pAb
    中文名称腺嘌呤核苷酸转运蛋白1、2、3、4抗体
    英文别名ATP carrier protein 1; ADP ATP carrier protein heart/skeletal muscle isoform T1; ADP/ATP translocase 1; ADT1_HUMAN; ANT 1; ANT; ANT1; ATP carrier protein 2; ADP ATP carrier protein heart/skeletal muscle isoform T2; ADP/ATP translocase 2; ADT2_HUMAN; ANT 2; ANT; ATP carrier protein 3; ADP ATP carrier protein heart/skeletal muscle isoform T3; ADP/ATP translocase 3; ADT3_HUMAN; ANT3; ATP carrier protein 4; ADP ATP carrier protein heart/skeletal muscle isoform T4; ADP/ATP translocase 4; ADT4_HUMAN; ANT 4; ANT4.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ANT1/2/3/4
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量33 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Found in a complex with ARL2, ARL2BP and SLC25A4. Interacts with ARL2BP (By similarity). Homodimer. Interacts with HIV-1 Vpr.
    亚细胞定位Mitochondrion inner membrane; Multi-pass membrane protein.
    相似性Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
    功能Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Defects in SLC25A4 are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant type 2 (PEOA2) [MIM:609283]. Progressive external ophthalmoplegia is characterized by progressive weakness of ocular muscles and levator muscle of the upper eyelid. In a minority of cases, it is associated with skeletal myopathy, which predominantly involves axial or proximal muscles and which causes abnormal fatigability and even permanent muscle weakness. Ragged-red fibers and atrophy are found on muscle biopsy. A large proportion of chronic ophthalmoplegias are associated with other symptoms, leading to a multisystemic pattern of this disease. Additional symptoms are variable, and may include cataracts, hearing loss, sensory axonal neuropathy, ataxia, depression, hypogonadism, and parkinsonism.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    ANT1+ANT2+ANT3+ANT4 Rabbit pAb
    P‌‌araformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ANT1+ANT2+ANT3+ANT4) Polyclonal Antibody, Unconjugated (bs-9567R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    ANT1+ANT2+ANT3+ANT4 Rabbit pAb
    Sample:
    Cerebrum (Mouse) Lysate at 40 ug
    Primary: Anti-ANT1+ANT2+ANT3+ANT4 (bs-9567R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 33 kD
    Observed band size: 33 kD

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    该产品被引用文献

    [IF={{ 8.469 }}] {Chen, Yan-Jie. et al. An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis. Cell Death Dis. 2022 Mar;13(3):1-16} {IHC} {Human}

    [IF={{ 1.5 }}] {Xue Liu. et al.Cuproptosis-related genes signature could predict prognosis and the response of immunotherapy in cervical cancer.translational cancer research.2025 Jan 31;14(1):129-140.} {IHC} {Human}

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    ANT1+ANT2+ANT3+ANT4 Rabbit pAb(bs-9567R)-50ul/100ul/200ul
    ￥1180 - 2800