SERPINB3 | SCCA1/T4-A Rabbit pAb(bs-9214R)-50ul/100ul/200ul产品图

SERPINB3 | SCCA1/T4-A Rabbit p

Ab(bs-9214R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-9214R
  • 2026年10月14日
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    • 规格:

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-9214R
    英文名称SERPINB3 Rabbit pAb
    中文名称丝氨酸蛋白酶抑制剂B3抗体
    英文别名HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine(or cysteine) proteinase inhibitor clade B(ovalbumin) member 3; Serpin B3; Serpin peptidase inhibitor clade B(ovalbumin) member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SERPINB3
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量46 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Tumor biomarkers > Enzymes

    Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors > Serine protease inhibitors > SERPINs

    Immunology > Immune System Diseases > Allergens

    亚细胞定位Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level.
    组织特异性Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).
    相似性Belongs to the serpin family. Ov-serpin subfamily.
    功能May act as a protease inhibitor to modulate the host immune response against tumor cells.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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    SERPINB3 | SCCA1/T4-A Rabbit pAb(bs-9214R)-50ul/100ul/200ul
    ¥1180 - 2800