Sample:
Fetal brain (Mouse) Lysate at 40 ug
Primary: Anti-DLL3 (bs-7860R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 65 kD
- ￥1180 - 2800
- Bioss
- bs-7860R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-7860R |
| 英文名称 | DLL3 Rabbit pAb |
| 中文名称 | Notch信号通路Delta样配体3抗体 |
| 英文别名 | delta Drosophila like 3; delta like 3 Drosophila; delta like 3 homolog Drosophila; delta like 3 protein; delta like protein 3 precursor; delta3; Drosophila delta homolog 3; SCDO1; Spondylocostal dysostosis autosomal recessive.DLL3_HUMAN |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Dog, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human DLL3 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 65 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Cell Cycle > Cell differentiation Developmental Biology > Embryogenesis > Somatogenesis Epigenetics and Nuclear Signaling > Cell cycle > Cell Differentiation Neuroscience > Neurology process > Notch Pathway |
| 亚基 | Can bind and activate Notch-1 or another Notch receptor (Probable). |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein (Probable). |
| 组织特异性 | Predominantly expressed in the neuroectoderm and paraxial mesoderm during embryogenesis. |
| 翻译后修饰 | Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. |
| 相似性 | Contains 1 DSL domain. Contains 6 EGF-like domains. |
| 功能 | Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Delta-like 3 (DLL3) is a transmembrane Delta-like protein that inhibits primary neurogenesis. It may be required to divert neurons along a specific differentiation pathway and plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 is one of five DSL proteins that bind to the Notch receptor and activates Notch signaling. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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[IF={{ 2.886 }}] {Xiao Fu. et al. PD-L1 Predicts Poor Prognosis in Surgically Resected Limited Stage Small-Cell Lung Cancer. Cancer Manag Res. 2020; 12: 10939–10948} {IHC} {Human}
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DLL3 Rabbit pAb(bs-7860R)-50ul/100ul/200ul
￥1180 - 2800
