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- bs-10297R
- 2025年10月24日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-10297R |
| 英文名称 | TRPV2 Rabbit pAb |
| 中文名称 | 辣椒素受体样蛋白1抗体 |
| 英文别名 | Osm 9 like TRP channel 2; Osm-9-like TRP channel 2; OTRPC2; Sac2b; Stretch activated channel 2B; Transient receptor potential cation channel subfamily V member 2; TrpV2; TRPV2_HUMAN; Vanilloid receptor like protein 1; Vanilloid receptor-like protein 1; VRL 1; VRL; VRL-1; VRL1. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TRPV2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 86 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300. |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > More Ion Channels Neuroscience > Neurotransmitter > Neuropeptides > More Neuropeptides Neuroscience > Sensory System > Somatosensory system > Nociception |
| 亚基 | Homotetramer. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Cytoplasm. Melanosome. |
| 翻译后修饰 | N-glycosylated.
Phosphorylated by PKA. |
| 相似性 | Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily. Contains 6 ANK repeats. |
| 功能 | Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 5.3 }}] {Jing Qiu. et al. PI3Kδ inhibition alleviates the brain injury during cerebral ischemia reperfusion via suppressing pericyte contraction in a TNF-α dependent manner. EXP NEUROL. 2024 May;375:114728} {IF,WB} {Mouse}
[IF={{ 4.014 }}] {Zhi Wang. et al. Differential expressions of hypothalamic thermosensitive TRP ion channels may underlie the post-hatching ontogeny of brain cooling capacity in broiler chickens. POULTRY SCIENCE. 2023 May;:102782} {WB} {Chicken}
[IF={{ 3.642 }}] {Ming-Chuang Sun. et al. ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2. INT J MED SCI. 2022; 19(6): 1072–1081} {WB} {Human}
[IF={{ 3.2 }}] {Xunrui Hou. et al. Investigation of local stimulation effects of embedding PGLA at Zusanli (ST36) acupoint in rats based on TRPV2 and TRPV4 ion channels. FRONT NEUROSCI-SWITZ. 2024 Oct;18:} {WB} {Rat}
[IF={{ 3.1 }}] {Yitong Zhou. et al. Protective Role of TRPV2 in Synaptic Plasticity Through the ERK1/2-CREB-BDNF Pathway in Chronic Unpredictable Mild Stress Rats. BIOCHEM BIOPH RES CO. 2024 May;:150128} {WB,IF} {Rat}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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