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产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-13242R |
| 英文名称 | G gamma12 Rabbit pAb |
| 中文名称 | G蛋白偶联受体γ12抗体 |
| 英文别名 | G-protein gamma-12 subunit; G gamma 12; GNG12; Guanine nucleotide binding protein(G protein) gamma 12; guanine nucleotide-binding protein G(I)/G(S)/G(O); Hypothetical protein DKFZp762E193; GBG12_HUMAN. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Dog, Pig, Cow, Horse) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human G gamma12 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 8 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚基 | G proteins are composed of 3 units, alpha, beta and gamma. |
| 亚细胞定位 | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). |
| 相似性 | Belongs to the G protein gamma family. |
| 功能 | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | G gamma12 has signal transducer activity in G-protein coupled receptor protein signaling pathway. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 5.738 }}] {Runze Liu. et al. GNG12 as A Novel Molecular Marker for the Diagnosis and Treatment of Glioma. FRONT ONCOL. 2022; 12: 726556} {IHC} {Human}
[IF={{ 5.3 }}] {Yang Lu. et al. Porphyromonas gingivalis induced UCHL3 to promote colon cancer progression. AM J CANCER RES. 2023; 13(12): 5981–5995} {WB} {Human}
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