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- Bioss
- bs-11212R
- 2025年10月16日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-11212R |
| 英文名称 | KLC1 Rabbit pAb |
| 中文名称 | 驱动蛋白2抗体 |
| 英文别名 | Kinesin 2 60/70kDa; Kinesin light chain 1; Kinesin2; Kinesin-2; KLC 1; KLC; KLC1; KLC1_HUMAN; KNS 2; KNS 2A; KNS2; KNS2A; Medulloblastoma antigen MU MB 2.50; MGC15245. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat (Chicken, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human KLC1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 65 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Cell Type Marker > Neuron marker > Axon marker Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin Signal Transduction > Protein Trafficking > Organelle Proteins |
| 亚基 | Belongs to the kinesin light chain family. Contains 6 TPR repeats. |
| 亚细胞定位 | Cytoplasm; cytoskeleton. |
| 组织特异性 | Found in a variety of tissues. Mostly abundant in brain and spine. |
| 翻译后修饰 | Isoform I is phosphorylated on Ser-600. Isoform J is phosphorylated on Ser-631. |
| 相似性 | Belongs to the kinesin light chain family. Contains 6 TPR repeats. |
| 功能 | Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The kinesin family of motor proteins comprise at least two forms of conventional kinesin (kinesin-I). They are encoded by different genes and designated ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells. Conventional kinesin is a heterotetramer of two kinesin heavy chain subunits and two kinesin light chain subunits. While the kinesin heavy chain contains motor activity, evidence suggests that the kinesin light chain is involved in either modulation of kinesin heavy chain activity or in cargo binding. The motor protein kinesin is a heterotetramer composed of two heavy chains and two light chains. Kinesin motor activity is dependent on the presence of ATP and microtubules. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
Lane 1: Mouse Testis tissue lysates
Lane 2: Mouse Placenta tissue lysates
Lane 3: Rat Testis tissue lysates
Lane 4: Rat Placenta tissue lysates
Lane 5: Human HepG2 cell lysates
Lane 6: Human 293T cell lysates
Lane 7: Human MCF-7 cell lysates
Lane 8: Human HeLa cell lysates
Primary: Anti-KLC1 (bs-11212R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kDa
Observed band size: 60 kDa
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文献和实验该产品被引用文献
[IF={{ 3.5 }}] {Zhaoxun Li. et al. Endoplasmic reticulum stress-related genes contribute to lung cancer risk: a multiomics data integration study. TRANSL LUNG CANCER R. 2025 Jun;14(6):2210} {IHC} {Human}
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KLC1 Rabbit pAb(bs-11212R)-50ul/100ul/200ul
￥1180 - 2800
