Sample:
Hela(Human) Cell Lysate at 30 ug
Primary: Anti- PDE3B (bs-8621R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 124 kD
Observed band size: 124 kD
- ￥1180 - 2800
- Bioss
- bs-8621R
- 2025年10月16日
- 产品信息以Bioss网站为准
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产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-8621R |
| 英文名称 | PDE3B Rabbit pAb |
| 中文名称 | 环核苷酸磷酸二酯酶PDE3B抗体 |
| 英文别名 | 5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP phosphodiesterase, adipocyte, cGMP-inhibited; CGI-PDE B; CGIP1; CGIPDE B; CGIPDE1; cGMP inhibited 3 5 cyclic phosphodiesterase B; CGMP inhibited cAMP phophodiesterase; cGMP-inhibited 3''; Cyclic GMP inhibited phosphodiesterase B; Cyclic GMP-inhibited phosphodiesterase B; Cyclic nucleotide phosphodiesterase; HcGIP1; HcGIP1, rat, homolog of; Pde3b; PDE3B_HUMAN; phosphodiesterase 3B cGMP inhibited. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Dog, Pig, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PDE3B |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 124 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Lipid metabolism Signal Transduction > Second Messenger > Nucleotide Messenger > cAMP Signal Transduction > Second Messenger > Nucleotide Messenger > cGMP |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Abundant in adipose tissues. |
| 相似性 | Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. |
| 功能 | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
K562(Human) Cell Lysate at 30 ug
Primary: Anti- PDE3B (bs-8621R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 124 kD
Observed band size: 124 kD
K562(Human) Cell Lysate at 30 ug
Primary: Anti- PDE3B (bs-8621R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 124 kD
Observed band size: 124 kD
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文献和实验该产品被引用文献
[IF={{ 7.419 }}] {Mingyan Shao. et al. Ginsenoside Rb3 upregulates sarcoplasmic reticulum Ca2+-ATPase expression and improves the contractility of cardiomyocytes by inhibiting the NF-κB pathway. BIOMED PHARMACOTHER. 2022 Oct;154:113661} {WB} {Mouse, Rat}
[IF={{ 15.8 }}] {Xingyuan Jiao. et al. Targeting the PDE3B-cAMP-autophagy axis prevents liver injury in long-term supercooling liver preservation. SCI TRANSL MED. 2024 Nov;16(775)} {WB} {Rat}
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PDE3B Rabbit pAb(bs-8621R)-50ul/100ul/200ul
￥1180 - 2800
