SLC20A2 Rabbit pAb(bs-8610R)-50ul/100ul/200ul

SLC20A2 Rabbit pAb(bs-8610R)-5

0ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-8610R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-8610R
    英文名称SLC20A2 Rabbit pAb
    中文名称溶质载体蛋白家族20成员2抗体
    英文别名Gibbon ape leukemia virus receptor 2; Gibbon leukemia virus receptor 2; GLVR 2; GLVR-2; GLVR2; hPit2; IBGC3; MLVAR; Murine leukemia virus amphotropic receptor; murine leukemia virus, amphotropic, receptor for; Phosphate transporter 2; PIT 2; PiT-2; Pit2; RAM1; S20A2_HUMAN; SLC20A2; Sodium-dependent phosphate transporter 2; Solute carrier family 20(phosphate transporter) member 2; solute carrier family 20(phosphate transporter), member 2; Solute carrier family 20 member 2.
    产品应用ICC/IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SLC20A2/PIT2
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量70 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Microbiology > Interspecies Interaction > Host Virus Interaction

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚基Homodimer.
    亚细胞定位Cell membrane.
    组织特异性Ubiquitously expressed.
    相似性Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
    功能Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The SLC20 family transport proteins were originally identified as retroviral receptors Glvr-1 and Ram-1, but are now designated sodium-dependent phosphate transporters 1 and 2 (PiT1 and PiT2). The PiT proteins function as sodium-phosphate cotransporters and are widely expressed, with high expression in bone, kidney and intestine. Both PiT1 and PiT2 are expressed on polarized epithelial cell membranes where they play a role in cellular phosphate homeostasis. PiT2 is a human receptor for amphotropic murine leukemia virus (A-MuLV). A-MuLV infects a variety of mammalian cell lines, including humans, making it a useful tool in gene transfer technology and as a vector for gene therapy. Retroviral vector systems are used in gene therapy that are designed to infect cells expressing PiT1 or PiT2.

     

    应用推荐稀释比例
    {ICC/IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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    SLC20A2 Rabbit pAb(bs-8610R)-50ul/100ul/200ul
    ¥1180 - 2800