- ￥1180 - 2800
- Bioss
- bs-13302R
- 2025年10月16日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
OAS2 Rabbit pAb, Biotin conjugated(bs-15588R-Bio)-100ul
￥2980Rad23 Rabbit pAb, APC-Cy5.5 conjugated(bs-7121R-APC-Cy5.5)-100ul
￥2980
CEACAM21 Rabbit pAb(bs-7996R)-50ul/100ul/200ul
￥1180
phospho-IKK gamma (Ser43) Rabbit pAb(bs-5393R)-50ul/100ul/200ul
￥1180CXCL13 Rabbit pAb, PerCP conjugated(bs-2553R-PerCP)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-13302R |
| 英文名称 | GBP1 Rabbit pAb |
| 中文名称 | G蛋白结合蛋白1抗体 |
| 英文别名 | GBP 1; GBP-1; GBP1; GBP1_HUMAN; GTP binding protein 1; GTP-binding protein 1; Guanine nucleotide binding protein 1; Guanine nucleotide-binding protein 1; Guanylate binding protein 1; Guanylate binding protein 1 interferon inducible 67kDa; Guanylate binding protein 1 interferon inducible; HuGBP 1; HuGBP-1; HuGBP1; Interferon induced guanylate binding protein 1; Interferon-induced guanylate-binding protein 1; OTTHUMP00000012352. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GBP1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 68 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Innate Immunity > Cytokines > Interferons Immunology > Innate Immunity > Macrophage / Inflamm. Signal Transduction > Second Messenger > Nucleotide Messenger > GTP |
| 亚基 | Homodimerizes upon GTP-binding, dimerization is required for the second hydrolysis step from GDP to GMP. Can also heterodimerize with other members of the family. |
| 亚细胞定位 | Cytoplasm. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor. |
| 相似性 | Belongs to the GBP family. |
| 功能 | Binds GTP, GDP and GMP. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Guanylate-binding proteins, GBP1 and GBP2 are GTP-binding proteins with a high-turnover GTPase activity and an antiviral effect (1-4). GBP1 mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus and plays a role in the IFN-mediated antiviral response against these viruses (4). GBP1 and GBP2 belong to a group of large GTP-binding proteins with a high concentration-dependent GTPase activity that have the common ability to undergo oligomerization (1). GBP1 and GBP2 are bone marrow-derived GTPases encoded by interferon-activated genes and are inducible following IFN treatment (2,3). Specifically, GBP1 is expressed in cultured mammary epithelial tumor cell lines after treatment with IFN-gamma and LPS. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验[IF={{ 3.829 }}] {Zhang Xiaohua. et al. Guanylate-binding protein 1 inhibits nuclear delivery of pseudorabies virus by disrupting structure of actin filaments. VET RES. 2023 Dec;54(1):1-12} {WB} {Mouse}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
技术资料暂无技术资料 索取技术资料
