Protein:spleen(mouse) lysate at 40ug;
Primary: rabbit Anti-EFHD2 (bs-14520R) at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
Predicted band size: 27 kD
Observed band size: 27 kD
- ￥1180 - 2800
- Bioss
- bs-14520R
- 2025年10月16日
- 产品信息以Bioss网站为准
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产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-14520R |
| 英文名称 | EFHD2 Rabbit pAb |
| 中文名称 | EFHD2蛋白抗体 |
| 英文别名 | EF hand domain containing protein 2; EF hand domain family, member D2; EF-hand domain-containing protein D2; EFHD 2; EFHD2; EFHD2_HUMAN; RP3-467K16.3; Swiprosin 1; Swiprosin-1; SWS1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Pig, Cow, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human EFHD2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 27 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Binding Proteins |
| 亚细胞定位 | Membrane raft. In immature B-cell line WEHI231. |
| 组织特异性 | Found in lymphocytes; preferentially expressed in CD8+ cells. |
| 相似性 | Contains 2 EF-hand domains. |
| 功能 | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | EFHD2 is a 240 amino acid protein that regulates spontaneous apoptosis through the regulation of Bcl-xS abundance. Localized to membrane raft, Swiprosin-1 is expressed in lymphocytes and contains two EF-hand domains. The gene encoding Swiprosin-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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EFHD2 Rabbit pAb(bs-14520R)-50ul/100ul/200ul
￥1180 - 2800
