MFNG | Manic Fringe Rabbit pAb(bs-12390R)-50ul/100ul/200ul产品图
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MFNG | Manic Fringe Rabbit pAb

(bs-12390R)-50ul/100ul/200ul
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  • ￥1180 - 2800
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  • bs-12390R
  • 2026年10月13日
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    北京博奥森生物技术有限公司
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    • 规格：

      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-12390R
    英文名称Manic Fringe Rabbit pAb
    中文名称狂躁基因同源蛋白MFNG抗体
    英文别名3-N-acetylglucosaminyltransferase manic fringe; beta-1; beta-1, 3-N-acetylglucosaminyltransferase manic fringe; MFNG; MFNG_HUMAN; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human, Mouse, Rat, Cow, Horse, Sheep, Chimpanzee)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Manic Fringe/MFNG
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量36 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Golgi apparatus membrane.
    相似性Belongs to the glycosyltransferase 31 family.
    功能Glycosyltransferase involved in the elongation of O-linked ligands to activate Notch signaling. Possesses fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical fringe plays a key role in the development of the limb bud. Lunatic fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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    图标文献和实验
    该产品被引用文献

    [IF=4.1] Tianshu Miao. et al. Down-regulation of MFNG promotes the metastatic potential of lung adenocarcinoma by regulating TGF-β/Smad signaling. ISCIENCE. 2025 Sep IHC Human

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    MFNG | Manic Fringe Rabbit pAb(bs-12390R)-50ul/100ul/200ul
    ￥1180 - 2800