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VEGFB Rabbit pAb(bs-10072R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-10072R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-10072R
    英文名称VEGFB Rabbit pAb
    中文名称血管内皮生长因子B
    英文别名Vascular endothelial growth factor B; VEGF B; VEGFB; VEGF-B; VEGF related factor; VEGFL; Vrf; vascular endothelial growth factor B isoform VEGFB-167 precursor; VEGFB_HUMAN.
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Dog, Pig, Cow, GuineaPig)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human VEGFB
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量22 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Growth factors > VEGF

    Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic growth factors

    Cardiovascular > Angiogenesis > Growth Factors > VEGF > VEGF

    Neuroscience > Neurology process > Neurogenesis

    Signal Transduction > Growth Factors/Hormones > VEGF

    亚基Homodimer; disulfide-linked. Can also form heterodimer with VEGF.
    亚细胞定位Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
    组织特异性Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
    翻译后修饰VEGF-B167 is O-glycosylated.
    相似性Belongs to the PDGF/VEGF growth factor family.
    功能The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described and include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs). The VEGF protein family is comprised of VEGF, VEGF-B, VEGF-C and VEGF-D, all of which may exhibit angiogenic function in vivo. VEGF-B, which exists as two alternatively spliced isoforms known as VEGF-B167 and VEGF-B186, is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF. VEGF-C binds to and specifically activates Flt-4 and Flk-1.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described and include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs). The VEGF protein family is comprised of VEGF, VEGF-B, VEGF-C and VEGF-D, all of which may exhibit angiogenic function in vivo. VEGF-B, which exists as two alternatively spliced isoforms known as VEGF-B167 and VEGF-B186, is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF. VEGF-C binds to and specifically activates Flt-4 and Flk-1.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

    产品细节图片1
    Blank control (blue line): A549 (fixed with 2% P‌‌araformaldehyde (10 min) , then permeabilized with 90% ice-cold methanol for 30 min on ice).
    Primary Antibody (green line): Rabbit Anti-VEGFB antibody (bs-10072R),Dilution: 1μg /10^6 cells;
    Isotype Control Antibody (orange line): Rabbit IgG .
    Secondary Antibody (white blue line): Goat anti-rabbit IgG-FITC,Dilution: 1μg /test.

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    ¥1180 - 2800