Sample:
Cerebrum (Rat) Lysate at 40 ug
Primary: Anti-FOXG1 (bs-11557R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
- ￥1180 - 2800
- Bioss
- bs-11557R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 详细信息
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- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-11557R |
| 英文名称 | FOXG1 Rabbit pAb |
| 中文名称 | 叉头蛋白G1抗体 |
| 英文别名 | BF 1; BF 2; BF-1; BF-2; BF1; BF2; Brain factor 1; Brain factor 2; FHKL; FKH2; FKHL1; FKHL2; FKHL2; FKHL3; FKHL4; Forkhead box G1A; Forkhead box G1B; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead drosophila homolog like 2; Forkhead like 1; Forkhead like 2; FOXG1_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Rat (Human, Mouse, Chicken, Dog, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human FOXG1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 52 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > FOXG Neuroscience > Neurology process > Neural Signal Transduction Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Interacts with KDM5B. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expression is restricted to the neurons of the developing telencephalon. |
| 相似性 | Contains 1 fork-head DNA-binding domain. |
| 功能 | Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (1–4). WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain (1,5,6). BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia (1). The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1,7). BF-1 is expressed by E8.5 in telencephalic progenitors (1). It may also regulate the response of cerebral cortical progenitors to environmental cues (1). |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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FOXG1 Rabbit pAb(bs-11557R)-50ul/100ul/200ul
￥1180 - 2800
