Angiopoietin-like 4 Rabbit pAb(bs-5919R)-50ul/100ul/200ul

Angiopoietin-like 4 Rabbit pAb

(bs-5919R)-50ul/100ul/200ul
收藏
  • ￥1180 - 2800
  • Bioss已认证
  • bs-5919R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-5919R
    英文名称Angiopoietin-like 4 Rabbit pAb
    中文名称血管生成素样蛋白4抗体
    英文别名Angiopoietin like 4; Angiopoietin related protein 4; Angiopoietin-like protein 4; Angiopoietin-related protein 4; ANGL4_HUMAN; ANGPT L2; ANGPT L4; ANGPTL2; ANGPTL4; ARP4; Fasting induced adipose factor; FIAF; Hepatic angiopoietin related protein; Hepatic fibrinogengiopoietin related protein; Hepatic fibrinogengiopoietin-related protein; HFARP; NL2; Peroxisome proliferator-activated receptor(PPAR) gamma induced angiopoietin related protein antibody PGAR; pp1158; PPARG angiopoietin related protein; PSEC0166; Weakly similar to angiopoietin 1 [H.sapiens].
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat, 肝, 肝, 肝, human renal cell carcinoma, human renal cell carcinoma (Dog, Pig, Cow, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ANGPTL4/ARP4
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量45 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins

    Cancer > Cancer Metabolism > Response to hypoxia

    Cardiovascular > Angiogenesis > Growth Factors

    Cardiovascular > Hypoxia > Hypoxia-Regulated

    Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cholesterol Metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Cholesterol Metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism

    Metabolism > Pathways and Processes > Metabolism processes > Hypoxia

    亚基Homooligomer. The homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix.
    亚细胞定位Secreted. Secreted, extracellular space, extracellular matrix.
    组织特异性Expressed at high levels in the placenta, heart, liver, muscle, pancreas and lung but expressed poorly in the brain and kidney.
    翻译后修饰N-glycosylated.
    相似性Contains 1 fibrinogen C-terminal domain.
    功能Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    Angiopoietin-like 4 Rabbit pAb
    P‌‌araformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Angiopoietin-like 4) Polyclonal Antibody, Unconjugated (bs-5919R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    Angiopoietin-like 4 Rabbit pAb
    P‌‌araformaldehyde-fixed, paraffin embedded (human liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Angiopoietin-like 4) Polyclonal Antibody, Unconjugated (bs-5919R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    Angiopoietin-like 4 Rabbit pAb
    P‌‌araformaldehyde-fixed, paraffin embedded (human heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Angiopoietin-like 4) Polyclonal Antibody, Unconjugated (bs-5919R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    Angiopoietin-like 4 Rabbit pAb
    P‌‌araformaldehyde-fixed, paraffin embedded (human renal cell carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Angiopoietin-like 4) Polyclonal Antibody, Unconjugated (bs-5919R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    Angiopoietin-like 4 Rabbit pAb
    Sample:
    Lane 1: Human 293T cell lysates
    Lane 2: Human HUVEC cell lysates
    Lane 3: Human HepG2 cell lysates
    Primary: Anti-Angiopoietin-like 4 (bs-5919R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 45 kDa
    Observed band size: 60 kDa
    Angiopoietin-like 4 Rabbit pAb
    P‌‌araformaldehyde-fixed, paraffin embedded (mouse kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (Angiopoietin-like 4) Polyclonal Antibody, Unconjugated (bs-5919R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    Angiopoietin-like 4 Rabbit pAb
    P‌‌araformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (Angiopoietin-like 4) Polyclonal Antibody, Unconjugated (bs-5919R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Angiopoietin 2 Rabbit pAb
    ￥600
    杭州戴格生物技术有限公司
    2025年07月14日询价
    Angiopoietin-like 4 Rabbit pAb
    询价
    上海圻明生物科技有限公司
    2025年07月12日询价
    Angiopoietin Like 4 Rabbit Monoclonal Antibody
    ￥1350
    武汉恩玑生命科技有限公司
    2025年07月07日询价
    Angiopoietin 1 Rabbit Monoclonal Antibody
    ￥980
    上海彩佑实业有限公司
    2025年07月12日询价
    Rabbit Monoclonal Antibody Angiopoietin Like 4
    ￥1280
    澳培赛生物科技（上海）有限公司
    2025年07月14日询价
    Angiopoietin-like 4 Rabbit pAb(bs-5919R)-50ul/100ul/200ul
    ￥1180 - 2800