CA2 | CA-II Rabbit pAb(bs-1709R)-50ul/100ul/200ul产品图
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CA2 | CA-II Rabbit pAb(bs-1709

R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-1709R
  • 2026年10月13日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-1709R
    英文名称CA II Rabbit pAb
    中文名称碳‌‌酸酐酶2抗体
    英文别名Carbonic anhydrase Ⅱ; CA 2; CA II; CA2; CAII; Car 2; Car2; Carbonate dehydratase II; Carbonic anhydrase 2; Carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; Carbonic dehydratase.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CA II
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量29 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Blood

    Cell Biology > Other Antibodies > Other Antibodies

    亚基Interacts with SLC4A4. Interaction with SLC4A7 regulates SLC4A7 transporter activity.
    亚细胞定位Cytoplasm.
    相似性Belongs to the alpha-carbonic anhydrase family.
    功能Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Carbonic anhydrase II (CAII) is a single polypeptide chain of molecular weight 29kDa. It is present in the cytosol of most tissues, but highest concentrations are found, like Carbonic Anhydrase I, in erythrocytes. The concentration in erythrocytes is about 20µM. It catalyses the hydration of CO2 and the hydrolysis of esters. Zn2+ ion cofactor is required for enzyme activity. Certain point mutations occur without apparent clinical effect, however, complete absence leads to mild mental retardation and cerebral calcification, osteoporosis and renal tubular acidosis. Also known as: Carbonic anhydrase Ⅱ; CA 2; CA II; CA2; CAII; Car 2; Car2; Carbonate dehydratase II; Carbonic anhydrase 2 ; Carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; Carbonic dehydratase.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    _x000D_ Bone (Mouse) Lysate at 40 ug
    _x000D_ Primary: Anti-CA II (bs-1709R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 29 kD
    _x000D_ Observed band size: 29 kD
    产品细节图片2
    Sample:
    _x000D_ Lane 1: Mouse Large intestine tissue lysates
    _x000D_ Lane 2: Mouse Spleen tissue lysates
    _x000D_ Lane 3: Mouse Kidney tissue lysates
    _x000D_ Lane 4: Mouse Cerebrum tissue lysates
    _x000D_ Lane 5: Rat Large intestine tissue lysates
    _x000D_ Lane 6: Rat Spleen tissue lysates
    _x000D_ Lane 7: Rat Kidney tissue lysates
    _x000D_ Lane 8: Rat Cerebrum tissue lysates
    _x000D_ Primary: Anti-CA II (bs-1709R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 29 kDa
    _x000D_ Observed band size: 30 kDa

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    图标文献和实验
    该产品被引用文献

    [IF=3.297] Hongyi Qu. et al. The effects of vasoactive intestinal peptide on RANKL-induced osteoclast formation. Ann Transl Med. 2021 Jan; 9(2): 127 WB Rat

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    CA2 | CA-II Rabbit pAb(bs-1709R)-50ul/100ul/200ul
    ¥1180 - 2800