Sample:
HepG2 Cell (Human) Lysate at 40 ug
293T Cell (Human) Lysate at 40 ug
Primary: Anti-glypican 3 (bs-1112R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 65 kD
- ￥1180 - 2800
- Bioss
- bs-1112R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-1112R |
| 英文名称 | Glypican 3 Rabbit pAb |
| 中文名称 | 磷脂酰基醇蛋白聚糖-3抗体 |
| 英文别名 | GPC3; glypican3; glypican-3; Intestinal protein OCI-5; GTR2-2; MXR7.Intestinal protein OCI-5; GPC3_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human glypican 3 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 65 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers Developmental Biology > Lineage specification > Mesoderm Signal Transduction > Cytoskeleton / ECM > HSPGs Stem Cells > Lineage Markers > Mesoderm |
| 亚细胞定位 | Cell membrane and Secreted, extracellular space. |
| 组织特异性 | Highly expressed in lung, liver and kidney. |
| 相似性 | Belongs to the glypican family. |
| 功能 | Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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[IF={{ 6.784 }}] {Jinno A et al. Syndecan-1 Promotes Streptococcus pneumoniae Corneal Infection by Facilitating the Assembly of Adhesive Fibronectin FibrilsmBio.2020 Dec 11;11(6):e02451-20.} {IHC} {Mouse}
[IF={{ 4.389 }}] {Jiuxin Zhu. et al. GPC3-targeted and curcumin-loaded phospholipid microbubbles for sono-photodynamic therapy in liver cancer cells. Colloid Surface B. 2021 Jan;197:111358} {IHC} {Human}
[IF={{ 3.715 }}] {Pavol Štefík. et al. Targeting acute myeloid leukemia cells by CD33 receptor-specific MoS2-based nanoconjugates. Biomed Mater. 2021 Jul;:} {WB} {}
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Glypican 3 Rabbit pAb(bs-1112R)-50ul/100ul/200ul
￥1180 - 2800
