Sample:
_x000D_
A549(Human) Cell Lysate at 30 ug
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293T(Human) Cell Lysate at 30 ug
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MDA-MB-231 (Human) Cell Lysate at 30 ug
_x000D_
Primary: Anti- ROR1 (bs-10076R) at 1/1000 dilution
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Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
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Predicted band size: 130 kD
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Observed band size: 130 kD
_x000D_
- ￥1180 - 2800
- Bioss
- bs-10076R
- 2026年10月13日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-10076R |
| 英文名称 | ROR1 Rabbit pAb |
| 中文名称 | 非酪氨酸蛋白激酶跨膜受体ROR1抗体 |
| 英文别名 | ROR1_HUMAN; Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; NTRKR1; receptor tyrosine kinase like orphan receptor 1; dJ537F10.1; |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Rat, Dog, Pig, Cow, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ROR1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 100 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurology process > Neurogenesis Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. |
| 相似性 | Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily._x000D_
Contains 1 FZ (frizzled) domain._x000D_ Contains 1 Ig-like C2-type (immunoglobulin-like) domain._x000D_ Contains 1 kringle domain._x000D_ Contains 1 protein kinase domain. |
| 功能 | Tyrosine-protein kinase receptor whose role is not yet clear. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF=6.8] Yang Zhang. et al. Development of Peptide Paratope Mimics Derived from the Anti-ROR1 Antibody and Long-Acting Peptide–Drug Conjugates for Targeted Cancer Therapy. J MED CHEM. 2024;XXXX(XXX):XXX-XXX IF Human
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ROR1 | NTRKR1 Rabbit pAb(bs-10076R)-50ul/100ul/200ul
￥1180 - 2800
