Sample:
Lane 1: Mouse Testis tissue lysates
Lane 2: Rat Testis tissue lysates
Primary: Anti-ADORA1 (bs-6649R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kDa
Observed band size: 36 kDa
- ￥1180 - 2800
- Bioss
- bs-6649R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-6649R |
| 英文名称 | ADORA1 Rabbit pAb |
| 中文名称 | 腺苷A1受体抗体 |
| 英文别名 | A1AR; A1R; AA1R; AA1R_HUMAN; Adenosine receptor A1; ADORA 1; ADORA1; RDC 7; RDC7; Ri. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human, Chicken, Dog, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ADORA1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 37 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell Death > Apoptosis > Receptors > Associated Proteins Cardiovascular > Atherosclerosis > Ischemia / Reperfusion Cardiovascular > Atherosclerosis > Vascular Inflammation > Inflammatory mediators Cardiovascular > Heart > Cardiac arrhythmias Cell Biology > Apoptosis > Receptors > Associated Proteins Immunology > Innate Immunity > Macrophage / Inflamm. Neuroscience > Neurology process > Neurogenesis Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNF?and blocks the endotoxin CD14 receptor signal transduction pathway. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 4.366 }}] {Aleix Martí Naviaet al. Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists. Cells . 2020 Jul 21;9(7):1739.} {IF} {rat}
[IF={{ 4.1 }}] {Dehua Huang. et al. Combining Metabolomics and Quantitative Analysis to Investigate Purine Metabolism Disorders in Depression and the Therapeutic Effect of Chaigui Granules. ACS CHEM NEUROSCI. 2025;XXXX(XXX):XXX-XXX} {WB} {Rat}
[IF={{ 3.565 }}] {Xu Lin. et al. ADORA1 is a diagnostic-related biomarker and correlated with immune infiltrates in papillary thyroid carcinoma. J Cancer. 2021; 12(13): 3997–4010} {IHC} {Human}
[IF={{ 2.942 }}] {Xue Gang. et al. Identification of key genes of papillary thyroid carcinoma by integrated bioinformatics analysis. Bioscience Rep. 2020 Aug;40(8):BSR20201555} {WB} {Human}
[IF={{ 2.34 }}] {Cao, Zhi-Ping, et al. "Effects of cordycepin on spontaneous alternation behavior and adenosine receptors expression in hippocampus." Physiology & Behavior (2017).} {IHC} {="Mouse"}
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ADORA1 Rabbit pAb(bs-6649R)-50ul/100ul/200ul
￥1180 - 2800
