Sample:
Lane 1: Spleen (Mouse) Lysate at 40 ug
Lane 2: Lymph node (Mouse) Lysate at 40 ug
Lane 3: Breast (Mouse) Lysate at 40 ug
Lane 4: Placenta (Mouse) Lysate at 40 ug
Lane 5: Skin (Mouse) Lysate at 40 ug
Lane 6: Spleen (Rat) Lysate at 40 ug
Lane 7: Lymph node (Rat) Lysate at 40 ug
Lane 8: Breast (Rat) Lysate at 40 ug
Lane 9: Skin (Rat) Lysate at 40 ug
Primary: Anti-IL22BP (bs-2625R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 48/44/28 kD
Observed band size: 42 kD
- ￥1180 - 2800
- Bioss
- bs-2625R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-2625R |
| 英文名称 | IL22BP Rabbit pAb |
| 中文名称 | 白介素22受体结合蛋白抗体 |
| 英文别名 | IL22RA2; Interleukin-22 receptor subunit alpha-2; IL-22 receptor subunit alpha-2; IL-22R-alpha-2; IL-22RA2; Interleukin-22-binding protein; IL-22BP; IL22BP; Cytokine receptor family 2 member 10; CRF2-10; Cytokine receptor class-II member 10; Cytokine receptor family type 2, soluble 1; CRF2-S1; ZcytoR16; I22R2_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human IL-22BP |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 28(hu)/25(mo, ra kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Innate Immunity > Cytokines > Interleukins |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach. |
| 相似性 | Belongs to the type II cytokine receptor family.
Contains 3 fibronectin type-III domains. |
| 功能 | Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | There are two isoforms of IL22 RA2 produce by alternative splicing. Isoform 1 may play a role in establishing and maintaining successful pregnancy. Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). It may play an important role as an IL22 antagonist in the regulation of inflammatory responses. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 4.087 }}] {Wang, Xiaobai. et al. Relationship between IL-22 and IL-22BP in diabetic cognitive dysfunction. ACTA DIABETOL. 2023 Jan;:1-14} {WB} {Mouse}
[IF={{ 0 }}] {Almishri, Wagdi. Regulatory Immune-Responses Occurring within the Liver Downstream of Hepatic iNKTcell activation. Diss. University of Calgary, 2015.} {IHC} {="Mouse"}
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= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
我的题目是鸡Mx基因的克隆，我的策略是先根据该基因家族(dynamin family)的氨基酸保守区设计简并引物克隆出该基因cDNA的部分片段，然后根据该片段序列设计基因特异性引物，利用RACE技术得到cDNA的3‘和5’末端，然后根据末端序列设计引物扩增出该基因全长cDNA. 我用简并引物从鸡cDNA中扩增出一个片段，约250bp, 测序后拿来BLAST时却发现，与之同源性最高的并不是其它的Mx基因，而是人的某一个基因，比对的结果中与该序列同源性较高的有人及鼠Mx基因，但是同源性并不
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IL22BP Rabbit pAb(bs-2625R)-50ul/100ul/200ul
￥1180 - 2800
