OTC Rabbit pAb(bs-6724R)-50ul/100ul/200ul

OTC Rabbit pAb(bs-6724R)-50ul/

100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-6724R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-6724R
    英文名称OTC Rabbit pAb
    中文名称鸟氨酸氨基甲酰转移酶抗体
    英文别名OCTD; Ornithine carbamoyltransferase mitochondrial; Ornithine Carbamoyltransferase; Ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; Otc; OTC_HUMAN; OTCase.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Dog, Pig, Cow, Horse)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human OTC
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量40 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Signal Transduction > Metabolism > Amino Acids

    Signal Transduction > Metabolism > Mitochondrial

    Tags & Cell Markers > Subcellular Markers > Organelles > Mitochondria

    亚基Homotrimer.
    亚细胞定位Mitochondrion matrix.
    组织特异性Mainly expressed in liver and intestinal mucosa.
    翻译后修饰Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.
    相似性Belongs to the ATCase/OTCase family.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    OTC Rabbit pAb(bs-6724R)-50ul/
    Sample: HepG2 Cell (Human) Lysate at 40 ug
    Primary: Anti-OTC (bs-6724R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 40 kD
    Observed band size: 45 kD

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    ¥1180 - 2800