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- bs-0984R
- 2025年10月24日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-0984R |
| 英文名称 | LHR Rabbit pAb |
| 中文名称 | 促黄体生成素受体抗体 |
| 英文别名 | LHCGR; Gonadotropin receptor; CGR; hCG receptor; FLJ41504; Gpcr19-rs1; GTHR-II; HHG; LCGR; LGR2; LH-R; LH/CG R; LH/CG-R; LH RECEPTOR; LH/CGR; LHRHR; LSH R; LSH-R; LSHR_MOUSE; Luteinizing hormone receptor; Luteinizing hormone/choriogonadotropin receptor; luteinizing hormone/choriogonadotropin receptor; Lutropin choriogonadotropic hormone receptor; Lutropin choriogonadotropic receptor; Lutropin-choriogonadotropic hormone receptor; ULG5. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Mouse, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse CG Receptor |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 76 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Endocrine system > Gonadotrophic axis Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Gonadal and thyroid cells. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 6 LRR (leucine-rich) repeats. Contains 1 LRRNT domain. |
| 功能 | Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Subcellular Location : Cell membrane; Multi-pass membrane protein. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 8.2 }}] {Qingjing Gao. et al. 1,25(OH)₂D₃ regulates androgen synthesis via transcriptional control of steroidogenic enzymes and LHR in the scented glands of muskrats (Ondatra zibethicus). FREE RADICAL BIO MED. 2025 Mar;229:82} {IHC} {Muskrat}
[IF={{ 6.71 }}] {Umehara, Takashi, et al. "The acceleration of reproductive aging in Nrg1flox/flox; Cyp19‐Cre female mice." Aging Cell (2017).} {IHC} {="Mouse"}
[IF={{ 6 }}] {Daniel R. Pfau. et al.Short and long duration testosterone treatments induce reversable subfertility in female mice using a gestational model of gender-affirming hormone therapy.human reproduction.2025 Feb 11:deaf016.} {IHC} {Mouse}
[IF={{ 4.161 }}] {Kinnear Hadrian M. et al. Presence of ovarian stromal aberrations after cessation of testosterone therapy in a transgender mouse model. BIOL REPROD. 2023 Feb;:} {IHC} {Mouse}
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