Sample: Lung(Mouse) lysate at 30ug;
Primary: Anti-Integrin alpha 3 (bs-2093R) at 1:300 dilution;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
Predicted band size: 20/114 kD
Observed band size: 20 kD
- ￥1180 - 2800
- Bioss
- bs-2093R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 详细信息
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- 应用范围：
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-2093R |
| 英文名称 | Integrin alpha 3 Rabbit pAb |
| 中文名称 | 整合素α3抗体 |
| 英文别名 | Integrin alpha 3 light chain; AA407068; Antigen identified by monoclonal; Integrin alpha-3; J143; CD49 antigen like family member C; CD49 antigen-like family member C; CD49c; CD49c antigen; FLJ34631; FLJ34704; FRP 2; FRP-2; FRP2; Galactoprotein B3; GAP B3; GAPB3; Integrin alpha 3; Integrin alpha-3 light chain; Integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor); ITA3_HUMAN; ITGA 3; Itga3; MSK18; VCA 2; VCA2; Very late activation protein 3 receptor alpha 3 subunit; VL3A; VLA 3 alpha chain; VLA 3 subunit alpha; VLA-3 subunit alpha; VLA3a. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat, Pig) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Integrin alpha 3 light chain |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 20/114 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Integrins > Alpha |
| 亚基 | Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-3 associates with beta-1. Interacts with HPS5. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells. |
| 翻译后修饰 | Isoform 1, but not isoform 2, is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. |
| 相似性 | Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. |
| 功能 | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample: Intestinal(Mouse) lysate at 30ug;
Primary: Anti-Integrin alpha 3 (bs-2093R) at 1:300 dilution;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
Predicted band size: 20/114 kD
Observed band size: 24 kD
Primary: Anti-Integrin alpha 3 (bs-2093R) at 1:300 dilution;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
Predicted band size: 20/114 kD
Observed band size: 24 kD
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Integrin alpha 3 Rabbit pAb(bs-2093R)-50ul/100ul/200ul
￥1180 - 2800
