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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-2725R |
| 英文名称 | Mast Cell Tryptase Rabbit pAb |
| 中文名称 | 肥大细胞类胰蛋白酶抗体 |
| 英文别名 | Tryptase delta; delta-tryptase; HmMCP-3-like tryptase III; Mast cell mMCP-7-like; Tryptase-3; TPSD1; MCP7L1; MMCP-7L; MCP7-LIKE; EC 3.4.21.59; MGC95428; TRYD; Tryptase3; alpha II; EC 3.4.21.59; Lung tryptase; Mast cell alpha II tryptase; Mast cell beta I tryptase; Mast cell protease 7; Mast cell protease II; MCP 7; MMCP 7; Pituitary tryptase; Skin tryptase; TPS 1; TPS1; TPS2; TPSAB1; TPSAB1 protein; TPSB1; Tryptase 1; Tryptase alpha 1; tryptase alpha I included; Tryptase alpha II; tryptase alpha II included; tryptase alpha included; tryptase alpha/beta 1; Tryptase beta 1; tryptase beta I included; Tryptase I; tryptase I included; Tryptase III; Tryptase skin; Tryptase beta-2; TRYB1_HUMAN; TRYB2_HUMAN; TRYD_HUMAN. |
| 产品应用 | ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TPSD1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 23 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Innate Immunity > Macrophage / Inflamm. Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Amino Acids |
| 亚基 | Homotetramer. |
| 亚细胞定位 | Secreted. Note=Released from the secretory granules upon mast cell activation. |
| 组织特异性 | Expressed in colon, lung, heart and synovial tissue. May be specific to mast cells. |
| 相似性 | Belongs to the peptidase S1 family. Tryptase subfamily._x000D_
Contains 1 peptidase S1 domain. |
| 功能 | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {ELISA} | {1:5000-10000} |
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文献和实验相关实验
that degrades laminin and type IV collagen and stimulates protease-activated receptor-2. J. Neurochem. (2000), 74(4), 1731�1738, Sawada, K. et al. 2. Purification of mast cell proteases from murine skin. Exp. Dermatol. (1999), 8(5), 413�418
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TPSAB1 | Mast Cell Tryptase Rabbit pAb(bs-2725R)-50ul/100ul/200ul
￥1180 - 2800
