Sample: Liver（Rat） lysate at 30ug;
Primary: Anti-alpha-Actinin-4 (bs-1505R) at 1:200 dilution;
Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1:3000 dilution;
Predicted band size : 40kD
Observed band size : 40kD
- ￥1180 - 2800
- Bioss
- bs-1505R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-1505R |
| 英文名称 | Vasohibin 1 Rabbit pAb |
| 中文名称 | 血管抑制蛋白1抗体 |
| 英文别名 | Vasohibin; KIAA1036; VASH; VASH; VASH1; VASH1_HUMAN; Vasohibin1; Vasohibin-1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Rat (Mouse, Dog, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human VASH1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 41 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Angiogenesis > Inhibitors |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Preferentially expressed in endothelial cells. Highly expressed in fetal organs. Expressed in brain and placenta, and at lower level in heart and kidney. Highly detected in microvessels endothelial cells of atherosclerotic lesions. |
| 翻译后修饰 | 2 major forms (42 and 36 kDa) and 2 minors (32 and 27 kDa)may be processed by proteolytic cleavage. The largest form (42 kDa)seems to be secreted and the other major form (63 kDa) seems toaccumulate within the cells or pericellular milieu. Polypeptideconsisting of Met-77 to Arg-318 may correspond to the 27 kDa formand that consisting of Met-77 to Val-365 may correspond to the 36kDa form. |
| 相似性 | Belongs to the vasohibin family. |
| 功能 | Angiogenesis inhibitor. Inhibits migration,proliferation and network formation by endothelial cells as well asangiogenesis. This inhibitory effect is selective to endothelialcells as it does not affect the migration of smooth muscle cells orfibroblasts. Does not affect the proliferation of cancer cells invitro, but inhibits tumor growth and tumor angiogenesis. Acts in anautocrine manner. Inhibits artery neointimal formation andmacrophage infiltration. Exhibits heparin-binding activity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | VASH1 is a angiogenesis inhibitor. It inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. It does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis and acts in an autocrine manner. VASH1 also inhibits artery neointimal formation and macrophage infiltration and exhibits heparin-binding activity. There are two named isoforms. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
A431(Human) Cell Lysate at 30 ug
Primary: Anti- Vasohibin 1 (bs-1505R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kD
Observed band size: 41 kD
A431(Human) Cell Lysate at 30 ug
Primary: Anti- Vasohibin 1 (bs-1505R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kD
Observed band size: 41 kD
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Vasohibin 1 Rabbit pAb(bs-1505R)-50ul/100ul/200ul
￥1180 - 2800
