Sample:
Lane 1: Mouse Heart tissue lysates
Lane 2: Mouse Adrenal gland tissue lysates
Lane 3: Rat Adrenal gland tissue lysates
Primary: Anti-CYP11B1 (bs-3898R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 50 kD
- ￥1180 - 2800
- Bioss
- bs-3898R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-3898R |
| 英文名称 | CYP11B1 Rabbit pAb |
| 中文名称 | 细胞色素P450 11B1抗体 |
| 英文别名 | CPN1; CYP11B; CYPXIB1; Cytochrome P450 11B1, mitochondrial; Cytochrome p450 XIB1; Cytochrome P450, family 11, subfamily B, polypeptide 1; FHI; P 450C11; P450C11; S11BH; Steroid 11 beta hydroxylase; Steroid 11 beta monooxygenase; C11B1_HUMAN; Cytochrome P-450c11; Cytochrome P450C11; Steroid 11-beta-hydroxylase. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CYP11B1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 55 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cytochromes Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism Metabolism > Pathways and Processes > Mitochondrial Metabolism > Cytochromes Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Signal Transduction > Growth Factors/Hormones > Hormones Signal Transduction > Metabolism > Mitochondrial |
| 亚细胞定位 | Mitochondrion membrane. |
| 组织特异性 | Mitochondrion membrane. |
| 相似性 | Belongs to the cytochrome P450 family. |
| 功能 | Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
SH-SY5Y (Human) Cell Lysate at 30 ug
Primary: Anti- CYP11B1 (bs-3898R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD
SH-SY5Y (Human) Cell Lysate at 30 ug
Primary: Anti- CYP11B1 (bs-3898R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD
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文献和实验该产品被引用文献
[IF={{ 8.2 }}] {Jin-Shan Li. et al. Salvianolic acid B drives gluconeogenesis and peroxisomal redox remodeling in cardiac ischemia/reperfusion injury: A metabolism regulation by metabolite signal crosstalk. FREE RADICAL BIO MED. 2025 Jan;:} {WB} {Rat}
[IF={{ 7.3 }}] {Vagnerová Karla. et al. Microbiota modulates the steroid response to acute immune stress in male mice. FRONT IMMUNOL. 2024 Feb;15:} {WB} {Mouse}
[IF={{ 4 }}] {Jing-Hang Jiang. et al.Human-like adrenal features in Chinese tree shrews revealed by multi-omics analysis of adrenal cell populations and steroid synthesis.zool res.2024 May 18;45(3):617-632.} {IHC} {Mouse}
[IF={{ 3.636 }}] {Nakanishi Tomoya. et al. Cortisol induces follicle regression, while FSH prevents cortisol-induced follicle regression in pigs. Mol Hum Reprod. 2021 May;:} {WB,IF} {Pig}
[IF={{ 2.348 }}] {Tyczewska et al. Expression of selected genes involved in steroidogenesis in the course of enucleation-induced rat adrenal regeneration. (2014) Int.J.Mol.Me. 33:613-23} {IHC} {Rat}
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CYP11B1 Rabbit pAb(bs-3898R)-50ul/100ul/200ul
￥1180 - 2800
