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| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-1825R |
| 英文名称 | Inhibin beta B Rabbit pAb |
| 中文名称 | 抑制素βB/Inhibin β B抗体 |
| 英文别名 | MGC157939; Activin A; Activin AB alpha polypeptide; Activin AB; Activin AB beta polypeptide; Activin B; Activin beta A chain; Activin beta B chain; ActivinA; ActivinAB; ActivinB; EDF; Erythroid differentiation protein; follicle stimulating hormone releasing protein; FRP; FSH releasing factor; FSH releasing protein; INHBA; INHBB; Inhibin; Inhibin beta 1; Inhibin beta 2; Inhibin beta A; Inhibin beta A chain; Inhibin beta A subunit; Inhibin beta B; Inhibin beta B chain; Inhibin beta B subunit; |
| 中文别名 | Inhibin βB. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat (Dog, Pig, Cow, Sheep, GuineaPig) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Inhibin beta B |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 13/45 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Endocrine system > Gonadotrophic axis Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis Signal Transduction > Growth Factors/Hormones > Hormones |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the TGF-beta family. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |

_x000D_ A431(Human) Cell Lysate at 40 ug
_x000D_ Primary: Anti- Inhibin beta B (bs-1825R) at 1/300 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 45 kD
_x000D_ Observed band size: 50 kD
_x000D_

_x000D_ Brain (Mouse) Lysate at 40 ug
_x000D_ Primary: Anti- Inhibin beta B (bs-1825R) at 1/300 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 45 kD
_x000D_ Observed band size: 50 kD
_x000D_


_x000D_ Lane 1: Mouse Testis tissue lysates
_x000D_ Lane 2: Mouse Breast tissue lysates
_x000D_ Lane 3: Mouse Placenta tissue lysates
_x000D_ Lane 4: Mouse Liver tissue lysates
_x000D_ Lane 5: Rat Testis tissue lysates
_x000D_ Lane 6: Rat Breast tissue lysates
_x000D_ Lane 7: Human A431 cell lysates
_x000D_ Lane 8: Human HepG2 cell lysates
_x000D_ Primary: Anti- Inhibin beta B (bs-1825R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 13/45 kDa
_x000D_ Observed band size: 46 kDa
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文献和实验[IF=4] Yucheng Shen. et al. Spinal cord injury–induced overflow incontinence reshapes the activin–follistatin–inhibin axis in mouse bladder and kidney. FRONT MOL BIOSCI. 2026 Feb;13:1752395 IF Mouse
[IF=3.998] A. Ikeda. et al. Follistatin expressed in mechanically-damaged salivary glands of male mice induces proliferation of CD49f + cells. Sci Rep-Uk. 2020 Nov;10(1):1-14 IHC Mouse
[IF=2.1] Kaisai Tuerxun. et al. Exploring the prognostic molecular mechanisms of medulloblastoma through methylation–transcriptome integration. SAGE OPEN MED. 2026 Jan IHC Human
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