FGF7 | KGF Rabbit pAb(bs-0734R)-50ul/100ul/200ul产品图
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FGF7 | KGF Rabbit pAb(bs-0734R

)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-0734R
  • 2026年10月13日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-0734R
    英文名称KGF Rabbit pAb
    中文名称纤维母细胞生长因子7抗体
    英文别名FGF 7; FGF7; FGF-7; Fibroblast Growth Factor 7; HBGF 7; HBGF7; HBGF-7; Keratinocyte growth factor precursor; Heparin binding growth factor 7; Keratinocyte Growth Factor; FGF7_HUMAN; Heparin-binding growth factor 7.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse, Chicken, Dog, Pig, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human KGF
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量18 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Interacts with FGFBP1. Interacts with FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
    亚细胞定位Secreted.
    组织特异性Epithelial cell.
    相似性Belongs to the heparin-binding growth factors family.
    功能Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    Tissue/cell: rat kidney tissue; 4% P‌‌araformaldehyde-fixed and paraffin-embedded;
    _x000D_ Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
    _x000D_ Incubation: Anti-KGF/FGF7 Polyclonal Antibody, Unconjugated(bs-0734R) 1:300, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
    _x000D_
    产品细节图片2
    P‌‌araformaldehyde-fixed, paraffin embedded (rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KGF) Polyclonal Antibody, Unconjugated (bs-0734R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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    图标文献和实验
    该产品被引用文献

    [IF=5.572] Haoming Chen. et al. Nicotine exposure exacerbates silica-induced pulmonary fibrosis via STAT3-BDNF-TrkB-mediated epithelial-mesenchymal transition in alveolar type II cells. FOOD CHEM TOXICOL. 2023 May;175:113694 WB,IHC Mouse,Human

    [IF=3.23] Cai, Yujiao, et al. "Keratinocyte growth factor improves epithelial structure and function in a mouse model of intestinal ischemia/reperfusion." PloS one7.9 (2012). WB ="Mouse"

    [IF=2.502] Pu J et al. FGF-7 facilitates the process of psoriasis by inducing TNF-α expression in HaCaT cells. Acta Biochim Biophys Sin (Shanghai). 2019 Sep 6;51(10):1056-1063. WB Mouse

    [IF=13.2] Nier Wu. et al. DNA nanotube-carrying antimicrobial peptide confers improved anti-infective therapy. NANO TODAY. 2024 Dec;59:102508 IF Mouse

    [IF=1.89] Cai, Yu-Jiao, et al. "Keratinocyte growth factor up-regulates Interleukin-7 expression following intestinal ischemia/reperfusion in vitro and in vivo." Int J Clin Exp Pathol 5.6 (2012): 569-580. WB ="Mouse"

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    FGF7 | KGF Rabbit pAb(bs-0734R)-50ul/100ul/200ul
    ¥1180 - 2800