Sele | Cd62E/ELAM1 Rabbit pAb(bs-1273R)-50ul/100ul/200ul产品图
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Sele | Cd62E/ELAM1 Rabbit pAb(

bs-1273R)-50ul/100ul/200ul
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  • ￥1180 - 2800
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  • bs-1273R
  • 2026年10月13日
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    北京博奥森生物技术有限公司
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    • 规格：

      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-1273R
    英文名称E-Selectin Rabbit pAb
    中文名称E选择素抗体
    英文别名CD 62E; CD26E; CD62E antigen; CD62 antigen-like family member E; E selectin; ELAM 1; ELAM; ELAM-1; ELAM1; Endothelial adhesion molecule 1; Endothelial leukocyte adhesion molecule 1; ESEL; LECAM 2; LECAM2; Leukocyte endothelial cell adhesion molecule 2; Leukocyte-endothelial cell adhesion molecule 2; LYAM2_HUMAN; SELE; Selectin E; SelectinE.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from mouse E-Selectin
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量65 kDa
    实际分子量115 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Angiogenesis > Endothelial Cell Markers

    Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment > Cell adhesion molecules

    Cardiovascular > Cardiovascular Markers > Cell Markers > Endothelial Cells

    Immunology > Cell Type Markers > CD > Adhesion

    Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Adhesion molecules ELISA kits

    Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > CD markers ELISA kits

    Stem Cells > Endothelial Progenitors > Endothelial Markers

    亚基Interacts with PSGL1/SELPLG through the sialyl Lewis X epitope. PSGL1 sulfation appears not to be required for this interaction.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    相似性Belongs to the selectin/LECAM family.
    Contains 1 C-type lectin domain.
    Contains 1 EGF-like domain.
    Contains 6 Sushi (CCP/SCR) domains.
    功能Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    P‌‌araformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with E-Selectin Polyclonal Antibody, Unconjugated (bs-1273R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
    产品细节图片2
    100 ng rhE-Selectin-His protein (bs-43646P) per lane probed with E-Selectin polyclonal antibody respectively, unconjugated (bs-1273R) at 1:1000 dilution and 4°C overnight incubation. Followed by corresponding conjugated secondary antibody incubation at r.t. for 60 min.

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    图标文献和实验
    该产品被引用文献
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    PMID:35155962ACS Omega2022-01-27
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    Sele | Cd62E/ELAM1 Rabbit pAb(bs-1273R)-50ul/100ul/200ul
    ￥1180 - 2800