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- bsm-33263M
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50ul/100ul/200ul/200ug
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 规格： | 200ug | 产品价格： | ￥5600.0 |
| 产品编号 | bsm-33263M |
| 英文名称 | PPAR delta Mouse mAb |
| 中文名称 | D型-过氧化酶活化增生受体单克隆抗体 |
| 英文别名 | FAAR; MGC3931; NR1C2; NUC1; NUCI; NUCII; Nuclear hormone receptor 1; Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferative activated receptor delta; Peroxisome proliferator-activated receptor beta(PPAR-beta); Peroxisome proliferator-activated receptor beta; Peroxisome proliferator-activated receptor delta; PPAR beta; PPAR-beta; PPAR-delta; PPAR-? PPARB; PPARD; PPARD_HUMAN. |
| 产品应用 | WB=1:500-2000, ICC/IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat) |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant human PPAR delta Protein |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 48 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Heart > Cardiac metabolism Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger Kits/ Lysates/ Other > Kits > Cell Metabolism Kits > Lipid Metabolism Kits > Fatty acids Metabolism > Types of disease > Obesity |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Ubiquitous with maximal levels in placenta and skeletal muscle. |
| 相似性 | Belongs to the nuclear hormone receptor family. NR1 subfamily._x000D_
Contains 1 nuclear receptor DNA-binding domain. |
| 功能 | Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Heterodimer with the retinoid X receptor. Subcellular located at nuclear Tissue specificity: Heart, adrenal and intestine. Belongs to the nuclear hormone receptor family. NR1 subfamily. It Contains 1 nuclear receptor DNA-binding domain. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {ICC/IF} | {1:100-500} |
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文献和实验该产品被引用文献
[IF=4.248] Lv Xiaoting. et al. αCGRP deficiency aggravates pulmonary fibrosis by activating the PPARγ signaling pathway. GENES IMMUN. 2023 May;:1-10 IHC,IF Rat，Mouse，Human
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PPARD | PPAR delta/beta Mouse mAb(bsm-33263M)-50ul/100ul/200ul/200ug
￥1180 - 5600
