SAMD8 Rabbit pAb(bs-19376R)-50ul/100ul/200ul

SAMD8 Rabbit pAb(bs-19376R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-19376R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-19376R
    英文名称SAMD8 Rabbit pAb
    中文名称SAMD8蛋白抗体
    英文别名1110053F04Rik; 1700010P07Rik; FLJ25082; MGC118303; RP11-487I5.5; SMSr; Sphingomyelin synthase related; Sphingomyelin synthase related protein 1; Sterile alpha motif domain containing 8.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Dog, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SAMD8
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量48 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Other Antibodies > Other Antibodies

    Signal Transduction > Metabolism > Lipid metabolism

    亚细胞定位Cytoplasmic and Nuclear.
    相似性Belongs to the sphingomyelin synthase family.
    功能Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料SAMD8 is a multi-pass membrane protein. It belongs to the sphingomyelin synthase family and contains 1 SAM (sterile alpha motif) domain. The function of the SAMD8 protein remains unknown.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    SAMD8 Rabbit pAb(bs-19376R)-50
    Sample:
    Heart(Mouse) Cell Lysate at 40 ug
    Primary: Anti-SAMD8 (bs-19376R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 48 kD
    Observed band size: 48 kD

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