Sample:
Lane 1: Skin (Mouse) Lysate at 40 ug
Lane 2: Uterus (Mouse) Lysate at 40 ug
Lane 3: Urinary bladder (Mouse) Lysate at 40 ug
Lane 4: Esophagus (Mouse) Lysate at 40 ug
Lane 5: Skin (Rat) Lysate at 40 ug
Lane 6: Uterus (Rat) Lysate at 40 ug
Lane 7: Urinary bladder (Rat) Lysate at 40 ug
Lane 8: Esophagus (Rat) Lysate at 40 ug
Primary: Anti-Cytokeratin 5 (bs-5352R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 62 kD
Observed band size: 60 kD
- ￥1180 - 2800
- Bioss
- bs-5352R
- 2025年10月24日
- 产品信息以Bioss网站为准
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产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-5352R |
| 英文名称 | pan-cytokeratin Rabbit pAb |
| 中文名称 | 广谱细胞角蛋白PCK抗体 |
| 英文别名 | P-CK; pan-cytokeratin; pan-CK; pan CK; CK-PAN; wide spectrum Cytokeratin; Cytokeratins; [CK4; CK75; CK3; CK2; CK6C; CK6A; keratin 6E]. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat (Dog, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human pan-cytokeratin |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class I > Cytokeratins |
| 亚细胞定位 | Cytoplasmic. |
| 组织特异性 | epithelial cells |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 5.7 }}] {Seiichiro Takao. et al. Near-infrared photoimmunotherapy in the models of hepatocellular carcinomas using cetuximab-IR700. CANCER SCI. 2023 Oct;:} {IHC} {Mouse}
[IF={{ 2 }}] {Qiong Lin. et al. Umbilical cord mesenchymal stem cells inhibited inflammation of bronchial epithelial cells by regulating Hedgehog pathway. EUR J HISTOCHEM. 2023 Oct 2; 67(4): 3908} {IF} {Human}
[IF={{ 1.4 }}] {Joung-Hee Kim. et al. Enhanced effect of the leaves extract from Prunus persica var. nucipersica on antioxidation, collagen synthesis, re-epithelialization and angiogenesis for the improvement of skin wound healing. BIOTECH HISTOCHEM. 2025 六月 13} {IHC} {Rat}
[IF={{ 1.1 }}] {Naoyuki FUKE. et al. Malignant myoepithelioma of the sublingual salivary gland in a Japanese Black cow. J VET MED SCI. 2025 四月 14} {IHC} {Cow}
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pan-cytokeratin Rabbit pAb(bs-5352R)-50ul/100ul/200ul
￥1180 - 2800
