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- bs-12589R
- 2025年10月24日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-12589R |
| 英文名称 | PDE9A Rabbit pAb |
| 中文名称 | 磷酸二酯酶9A抗体 |
| 英文别名 | 5''-cyclic phosphodiesterase 9A; cGMP specific 3' 5' cyclic phosphodiesterase type 9; CGMP-specific 3'5'-cyclic phosphodiesterase type 9; FLJ90181; High affinity cGMP-specific 3''; High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A; HSPDE9A2; OTTHUMP00000109399; PDE 9A; Pde9a; PDE9A_HUMAN; phosphodiesterase 9A; phosphodiesterase PDE9A21. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Pig, Cow, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PDE9A |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 70-73 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Second Messenger > Nucleotide Messenger > cAMP Signal Transduction > Second Messenger > Nucleotide Messenger > cGMP |
| 亚细胞定位 | Cytoplasm. Endoplasmic reticulum; Cell projection > ruffle membrane. Cytoplasm > perinuclear region and Cell projection > ruffle membrane. Cytoplasm > perinuclear region. Golgi apparatus. Endoplasmic reticulum. |
| 组织特异性 | Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate. |
| 相似性 | Belongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily. |
| 功能 | Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PDE9A) Polyclonal Antibody, Unconjugated (bs-12589R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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PDE9A Rabbit pAb(bs-12589R)-50ul/100ul/200ul
￥1180 - 2800
