Sample: Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-SIRT4 (bs-7537R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 32 kD
- ￥1180 - 2800
- Bioss
- bs-7537R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-7537R |
| 英文名称 | SIRT4 Rabbit pAb |
| 中文名称 | 沉默调节相关蛋白4抗体 |
| 英文别名 | NAD dependent deacetylase sirtuin 4; NAD-dependent ADP-ribosyltransferase sirtuin-4; Silent mating type information regulation 2 homolog; Sir 2 like 4; SIR 2 like protein 4; Sir2 like 4; SIR2 like protein 4; SIR2-like protein 4; SIR2L 4; SIR2L4; SIRT 4; Sirt4; SIRT4_HUMAN; Sirtuin(silent mating type information regulation 2 homolog) 4; Sirtuin(silent mating type information regulation 2 homolog) 4(S. cerevisiae); Sirtuin 4; Sirtuin type 4; Sirtuin4. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, Fruit Fly) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SIRT4/SIR 2 like protein 4 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 32 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Atherosclerosis > Diabetes associated Cardiovascular > Heart > Cardiac metabolism Cell Biology > Other Antibodies > Other Antibodies Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Acetylation > HDACs > Class III / Sir2 class Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > ADP-ribosylation Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Types of disease > Cancer Metabolism > Types of disease > Diabetes Metabolism > Types of disease > Heart disease Signal Transduction > Metabolism > Energy Metabolism |
| 亚基 | Interacts with GLUD1, IDE and SLC25A5. |
| 亚细胞定位 | Mitochondrion matrix. |
| 组织特异性 | Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus. |
| 相似性 | Belongs to the sirtuin family. Class II subfamily.
Contains 1 deacetylase sirtuin-type domain. |
| 功能 | NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 6.317 }}] {Ai-Wen Kang. et al. Puerarin extends the lifespan of Drosophila melanogaster by activating autophagy. FOOD FUNCT. 2023 Feb;:} {WB} {Drosophila melanogaster}
[IF={{ 10.787 }}] {Chih-Chang Chao. et al. SRT1720 as an SIRT1 activator for alleviating paraquat-induced models of Parkinson's disease. REDOX BIOL. 2022 Dec;58:102534} {WB} {Human}
[IF={{ 1.11 }}] {Takumida, Masaya, Hiroshi Takumida, and Matti Anniko. "Localization of sirtuins in the mouse inner ear." Acta Oto-Laryngologica 0 (2014): 1-8.} {IHC} {="Mouse"}
[IF={{ 1.1 }}] {Takumida, Masaya, et al. "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." Acta oto-laryngologica (2015): 1-12.} {Other} {=""}
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SIRT4 Rabbit pAb(bs-7537R)-50ul/100ul/200ul
￥1180 - 2800
