ZFR Rabbit pAb(bs-19137R)-50ul/100ul/200ul

ZFR Rabbit pAb(bs-19137R)-50ul

/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-19137R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-19137R
    英文名称ZFR Rabbit pAb
    中文名称锌指RNA结合蛋白抗体
    英文别名FLJ41312; hZFR; M phase phosphoprotein homolog; M-phase phosphoprotein homolog; zfr; ZFR_HUMAN; zinc finger RNA binding protein; Zinc finger RNA-binding protein.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ZFR
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量117 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    亚细胞定位Nucleus. Cytoplasm. Cytoplasmic granule. Chromosome. Associated with chromosome foci in meiotic cells. Localizes in somatodendritic compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules.
    组织特异性Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney.
    相似性Contains 1 DZF domain.
    功能Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料ZFR is 1,074 amino acid RNA-binding protein. In human, ZFR is expressed in lung, liver, lymphocytes, heart, pancreas, kidney and placenta, and regulates postimplantation and gastrulation stages of development. Murine ZFR is observed in testis, ovary and brain. With elevated levels of expression during meiosis, ZFR associates with chromosome foci in meiotic cells. ZFR contains 1 DZF domain and localizes in the somatodendritic compartment of hippocampal neurons and colocalizes with STAU2 in cytosolic RNA granules. Knockout of ZFR in mouse embryo prevents the development of some embryonic structures leads to an increase in programmed cell death with a decrease in mitotic index.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    ZFR Rabbit pAb(bs-19137R)-50ul
    Sample:
    Lane 1: Siha (Human) Cell Lysate at 30 ug
    Lane 2: HL60 (Human) Cell Lysate at 30 ug
    Lane 3: K562 (Human) Cell Lysate at 30 ug
    Lane 4: Hela (Human) Cell Lysate at 30 ug
    Primary: Anti-ZFR (bs-19137R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 117 kD
    Observed band size: 117 kD

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