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- bs-18298R
- 2025年10月16日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-18298R |
| 英文名称 | LIPT1 Rabbit pAb |
| 中文名称 | 硫辛酰连接酶抗体 |
| 英文别名 | Lipoate biosynthesis protein; Lipoate-protein ligase; Lipoyl ligase; Lipoyltransferase 1; Lipoyltransferase 1 mitochondrial; LIPT_HUMAN; Lipt1; mitochondrial. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human LIPT1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 41 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Mitochondrion. |
| 组织特异性 | Highly expressed in skeletal muscle and heart, moderately in kidney and pancreas, and detected at lower levels in liver, brain, placenta and lung. |
| 相似性 | Belongs to the lplA family. |
| 功能 | Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neiGHBoring downstream mitochondrial ribosomal protein L30 (MRPL30) gene. [provided by RefSeq, Mar 2011] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验[IF={{ 8.786 }}] {Mingyi Yang. et al. A novel signature to guide osteosarcoma prognosis and immune microenvironment: Cuproptosis-related lncRNA. FRONT IMMUNOL. 2022; 13: 919231} {WB,IHC} {Human}
[IF={{ 5.6 }}] {Yang Xiaolin. et al. Cuproptosis-related genes signature and validation of differential expression and the potential targeting drugs in temporal lobe epilepsy. FRONT PHARMACOL. 2023 Jun;14:} {IHC} {Human}
[IF={{ 3.5 }}] {Xiaoxuan Zhao. et al. Demystifying the Landscape of Endometrial Immune Microenvironment in Luteal-Phase from Cuprotosis: Implications for the Mechanism and Treatment of RPL. GENE. 2024 Jan;:148191} {IF} {Mouse}
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