phospho-IL13RA1 (Tyr405) Rabbit pAb(bs-18135R)-50ul/100ul/200ul

phospho-IL13RA1 (Tyr405) Rabbi

t pAb(bs-18135R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-18135R
  • 2025年10月16日
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-18135R
    英文名称phospho-IL13RA1 (Tyr405) Rabbit pAb
    中文名称磷酸化白细胞介素13受体α1抗体
    英文别名IL13 receptor alpha 1(phospho Y405); p-IL13 receptor alpha 1(phospho Y405); I13R1_HUMAN; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19(CT19); CD213a1; IL13R, IL13RA; NR4; CT19; CD213A1; IL-13Ra;
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Pig, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated Synthesised phosphopeptide derived from human IL13 receptor alpha 1 around the phosphorylation site of Tyr405
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量42 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Innate Immunity > Cytokines > Interleukins

    Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases

    亚基Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. Interacts with TRAF3IP1.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Spleen, liver, thymus, heart, lung, kidney, testis, stomach, brain, skin, and colon; but not skeletal muscle.
    相似性Belongs to the type I cytokine receptor family. Type 5 subfamily.
    功能Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    phospho-IL13RA1 (Tyr405) Rabbi
    Sample:
    Heart (Mouse) Lysate at 40 ug
    Liver (Mouse) Lysate at 40 ug
    Primary: Anti-p-IL13receptor alpha 1 (Tyr405) (bs-18135R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 42 kD
    Observed band size: 42 kD

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    phospho-IL13RA1 (Tyr405) Rabbit pAb(bs-18135R)-50ul/100ul/200ul
    ¥1180 - 2800