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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-19621R |
| 英文名称 | PADI3 / PAD3 Rabbit pAb |
| 中文名称 | 蛋白质精氨酸亚型3抗体 |
| 英文别名 | PADI3_HUMAN; Protein-arginine deiminase type-3; EC:3.5.3.15; Peptidylarginine deiminase III; Protein-arginine deiminase type III; PDI3; UHS1; |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PADI3 / PAD3 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 75 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Arginine Deiminases Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Methylation > Arginine Deimination Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism Signal Transduction > Metabolism > Amino Acids |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Hair follicles, and epidermis at very low levels. |
| 相似性 | Belongs to the protein arginine deiminase family. |
| 功能 | Catalyzes the deimination of arginine residues of proteins. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

_x000D_ Liver (Mouse) Lysate at 40 ug
_x000D_ Primary: Anti-PADI3 / PAD3 (bs-19621R) at 1/300 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 75 kD
_x000D_ Observed band size: 75 kD
_x000D_

_x000D_ Pancreas (Mouse) Lysate at 40 ug
_x000D_ Primary: Anti-PADI3 / PAD3 (bs-19621R) at 1/300 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 75 kD
_x000D_ Observed band size: 75 kD
_x000D_
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文献和实验[IF=2.5] Shaohai He. et al. A four-gene amino acid metabolism signature predicts prognosis, immune infiltration, and chemotherapy response in oral squamous cell carcinoma. J RADIAT RES APPL SC. 2025 Dec;18:102028 IHC Human
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