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- 2025年10月16日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-18440R |
| 英文名称 | LTBP2/C14orf141 Rabbit pAb |
| 中文名称 | 潜在型TGF-β结合蛋白2抗体 |
| 英文别名 | C14orf141; Chromosome 14 open reading frame 141; Latent TGF beta binding protein 2; Latent transforming growth factor beta binding protein 2; Latent-transforming growth factor beta-binding protein 2; LTBP 2; LTBP 3; LTBP-2; Ltbp2; LTBP2_HUMAN; LTBP3; MSTP 031; MSTP031. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human LTBP2/C14orf141 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 191 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Growth Factors/Hormones > TGF Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation |
| 亚细胞定位 | Secreted. Localized in nuchal ligament and aorta to the fibrillin-containing, microfibrillar component of elastic fibers. |
| 组织特异性 | Expressed in lung, weakly expressed in heart, placenta, liver and skeletal muscle. |
| 翻译后修饰 | Contains hydroxylated asparagine residues. |
| 相似性 | Belongs to the LTBP family. Contains 20 EGF-like domains. Contains 4 TB (TGF-beta binding) domains. |
| 功能 | May play an integral structural role in elastic-fiber architectural organization and/or assembly. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 42.5 }}] {Yingjie Ding. et al. Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures. CELL. 2025 七月 25} {IHC} {Human}
[IF={{ 3.4 }}] {Gao Lun. et al. Integrated bioinformatics analysis and experimental validation on malignant progression and immune cell infiltration of LTBP2 in gliomas. BMC CANCER. 2024 Dec;24(1):1-15} {IF,WB} {Human}
[IF={{ 3.258 }}] {Hang Li. et al. Identification of Potential Pathogenic Super-Enhancers-Driven Genes in Pulmonary Fibrosis. Front Genet. 2021; 12: 644143} {IF} {Mouse}
[IF={{ 0 }}] {William J. Burlingham. et al. Extracellular Vesicle–associated GARP/TGFβ:LAP Mediates “Infectious” Allo-tolerance. TRANSPLANT DIRECT. 2023 Jun; 9(6): e1475} {ELISA} {Mouse}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
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【资源】全面归类网址：毕赤酵母表达各种来源蛋白（细菌，真菌，植物，人类等）
brasiliensis (parasitic nematode) non-neuronal secreted acetylcholinesteraseS, 50mg/L, α-MF, active[141, 354]Olea europaea Ole e 9 C-teminalPanulirus argus (spiny lobster) cytochrome P-450I, 20 pmol/mg microsomal prot., active351Pseudaletia separata (armyworm
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