MIR16 Rabbit pAb(bs-12039R)-50ul/100ul/200ul

MIR16 Rabbit pAb(bs-12039R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-12039R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-12039R
    英文名称MIR16 Rabbit pAb
    中文名称膜蛋白相互作用蛋白GDE1 (MIR16) 抗体
    英文别名GDE1; GDE1_HUMAN; EC 3.1.4.44; Glycerophosphodiester phosphodiesterase 1; Glycerophosphoinositol glycerophosphodiesterase GDE1; Membrane interacting protein of RGS16; Membrane-interacting protein of RGS16; RGS16 interacting membrane protein; RGS16-interacting membrane protein; Lysophospholipase D GDE1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Dog, Pig, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human MIR16/GDE1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量38 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Interacts with RGS16. Interacts with PRAF2.
    亚细胞定位Cytoplasmic. Membrane; Multi-pass membrane protein.
    组织特异性Widely expressed.
    翻译后修饰N-glycosylated
    相似性Belongs to the glycerophosphoryl diester phosphodiesterase family.
    Contains 1 GDPD domain.
    功能MIR6 has glycerophosphoinositol phosphodiesterase activity.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    MIR16 Rabbit pAb(bs-12039R)-50
    Sample:
    Kidney (Mouse) Lysate at 40 ug
    Primary: Anti- MIR16 (bs-12039R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 38 kD
    Observed band size: 40 kD

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