Sample:
_x000D_
A549(Human) Cell Lysate at 30 ug
_x000D_
U87MG(Human) Cell Lysate at 30 ug
_x000D_
MOLT-4(Human) Cell Lysate at 30 ug
_x000D_
Primary: Anti- phospho-ATP citrate lyase (Ser455) (bs-3037R) at 1/1000 dilution
_x000D_
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_
Predicted band size: 122 kD
_x000D_
Observed band size: 122 kD
_x000D_
- ￥1180 - 2800
- Bioss
- bs-3037R
- 2026年10月13日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
源叶生物 十万种现货试剂速发，品质稳、品类全，实验不再等！Takara 秋促来袭，提取+反转录+定量套装仅 1200 元abinScience 体内级抗体 全年锁价 低至 ￥1200阿拉丁 22万+ 科研级产品现货速发，品质严控、科研无忧- 详细信息
- 文献和实验
- 技术资料
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-3037R |
| 英文名称 | phospho-ACLY (Ser455) Rabbit pAb |
| 中文名称 | 磷酸化三磷酸腺柠檬酸裂解酶抗体 |
| 英文别名 | ATP citrate lyase(phospho S455); ACL; ATP citrate(pro-S) lyase; ATP citrate synthase; Citrate cleavage enzyme; EC 2.3.3.8; A730098H14RIK; ACLY; ATP CITRATE LYASE; ATPCL; AW538652; Cce; CITRATE LYASE; CLATP; MGC124629; ACL; ACLY_HUMAN; ATP citrate lyase; ATP-citrate(pro-S-)-lyase; ATP-citrate synthase; ATPcitrate synthase; |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated Synthesised phosphopeptide derived from human ACLY around the phosphorylation site of Ser455 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 122 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Energy Metabolism Signal Transduction > Metabolism > Lipid metabolism |
| 亚基 | Homotetramer. |
| 亚细胞定位 | Cytoplasm. |
| 翻译后修饰 | ISGylated._x000D_
Acetylated at Lys-540, Lys-546 and Lys-554 by KAT2B/PCAF. Acetylation is promoted by glucose and stabilizes the protein, probably by preventing ubiquitination at the same sites. Acetylation promotes de novo lipid synthesis. Deacetylated by SIRT2._x000D_ Ubiquitinated at Lys-540, Lys-546 and Lys-554 by UBR4, leading to its degradation. Ubiquitination is probably inhibited by acetylation at same site. |
| 相似性 | In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family._x000D_
In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. |
| 功能 | ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验相关实验
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
TnT rabbit reticulocyte lysate DEPC‐treated (nuclease‐free) H 2 O (Promega, cat. no. P1193
Models and Analysis of Atherosclerosis, Restenosis, and Aneurysm Formation in the Mouse
Kanters, E., Pasparakis, M., Gijbels, M.J., Vergouwe, M.N., Partouns‐Hendriks, I., Fijneman, R.J., Clausen, B.E., Förster, I., Kockx, M.M., Rajewsky, K., Kraal, G., Hofker, M.H., and de Winther, M.P. 2003. Inhibition of NF‐kappaB activation
技术资料暂无技术资料 索取技术资料
ACLY (p-S455) Rabbit pAb(bs-3037R)-50ul/100ul/200ul
￥1180 - 2800
