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- 详细信息
- 技术资料
- 保存条件:
-20°C
- 保质期:
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2190℃ for several months.
- 英文名:
Wiskostatin
- 库存:
详询
- 供应商:
详询
- CAS号:
253449-04-6
- 规格:
2mg/5mg/10mg/25mg/50mg/1ml/10mM
| 规格: | 2mg | 产品价格: | ¥610.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥1414.0 |
| 规格: | 10mg | 产品价格: | ¥2320.0 |
| 规格: | 25mg | 产品价格: | ¥3780.0 |
| 规格: | 50mg | 产品价格: | ¥5660.0 |
| 规格: | 1ml/10mM | 产品价格: | ¥1200.0 |
ID:T2164
PURITY:97%+
Formula:C17H18Br2N2O
MolWt:426.15
Appearance:白色粉末
Solubility:G410 mM in DMSO
Bioactivity:Wiskott-Aldrich syndrome protein (WASP) and WAVE stimulate actin-related protein (Arp)2/3-mediated actin polymerization, leading to diverse downstream effects, including the formation and remodeling of cell surface protrusions, modulation of cell migration, and intracytoplasmic propulsion of organelles and pathogens. Selective inhibitors of individual Arp2/3 activators would enable more exact dissection of WASP- and WAVE-dependent cellular pathways and are potential therapeutic targets for viral pathogenesis. Wiskostatin is a recently described chemical inhibitor that selectively inhibits neuronal WASP (N-WASP)-mediated actin polymerization in vitro.
Status:undetermined
Pathways:Cell Cycle/Checkpoint
Target:N-WASP inhibitor
Receptor:WASP;(Arp)2/3
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