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- 文献和实验
- 技术资料
- 保存条件:
-20°C
- 保质期:
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2180℃ for several months.
- 英文名:
1NM-PP1
- 库存:
详询
- 供应商:
详询
- CAS号:
221244-14-0
- 规格:
2mg/5mg/10mg/50mg/1ml/10mM
| 规格: | 2mg | 产品价格: | ¥585.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥789.0 |
| 规格: | 10mg | 产品价格: | ¥1188.0 |
| 规格: | 50mg | 产品价格: | ¥3541.0 |
| 规格: | 1ml/10mM | 产品价格: | ¥1088.0 |
ID:T2153
PURITY:97%+
Formula:C20H21N5
MolWt:331.41
Appearance:白色粉末
Solubility:G410 mM in DMSO
Bioactivity:1NM-PP1(PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors(IC50=28 uM vSrc; 4.2 nM v-Src-as1 I338G).
Status:
Pathways:Tyrosine Kinase/Adaptors
Target:Src inhibitor
Receptor:Src Family Kinase
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文献和实验lingwu 酪氨酸激酶抑制剂PP1和PP2有什么区别?如何选择, 急切想知道,谢谢! ylhuang0502 首先纠正一下, PP1和PP2都不是酪氨酸激酶的通用抑制剂,两者均为Src family kinase的选择性抑制剂。其中PP2更常用些,两者的差异很小,化学结构非常相似,两者均不是Src family kinase 特异性抑制剂,两者均可抑制别的激酶的活性,,比如: The Src
Interaction Between the Retinoblastoma Protein and Protein Phosphatase 1 During the Cell Cycle
) of protein phosphatase 1 (PP1) in controlling pRb are only partially understood. In this chapter, we will describe experimental approaches to investigate the interactions between pRb and PP1. Methods will be presented to study the cell cycle-dependent
此仪器可用来对透明或半透明固体和液体物质的折射率,平均色散和部分色散进行快速精确地测定(即能测定706.5nm、656.3nm、589.3nm、546.1nm、486.1nm、435.8nm、434.1nm和404.7nm等八种常用波长的折射率)。当光学玻璃牌号已知可以很快地测得其折射率,这些数据对光学仪器的设计和制造是极为有用的。一般仪器在测量试样折射率时需要有一定大小,而此仪器利用精确配制浸液法可求得最小试样的折射率,对保护被测试样是尤为重要的。由于此仪器基于折射定律的原理,所以被测试
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